TỶ LỆ THIỂU CƠ VÀ CÁC YẾU TỐ LIÊN QUAN Ở BỆNH NHÂN BỆNH THẬN MẠN: MỘT NGHIÊN CỨU CẮT NGANG

Abstract

Background: Sarcopenia is common in CKD and portends adverse outcomes. Local data on correlates with age, BMI, kidney function and performance measures are limited. Objective: To estimate sarcopenia prevalence and analyze associated factors in CKD. Methods: Cross-sectional study of 101 adults with CKD. Variables included age, sex, CKD duration, BMI, albumin-to-creatinine ratio, eGFR categories (G1–G5), skeletal muscle index (SMI), appendicular skeletal muscle (ASM), percent body fat, handgrip strength and gait speed. Comparative and correlation analyses were performed. Results: Median age was 67 with 40.6% male. The eGFR G3b group was predominated and albuminuria A3 was most frequent. Sarcopenia prevalence was 33.7% with no sex difference. Sarcopenic patients were older (median age 70 vs. 65; p < 0,05) and had lower BMI ((21,7 ± 2,2 vs. 25,5 ± 2,9 kg/m²; p < 0,001). Handgrip strongly correlated with SMI (r = 0.694; p < 0.001) and inversely with gait time (r = −0.542; p < 0.001); SMI inversely correlated with gait time (r = −0.458; p < 0.001). Conclusion: About one-third of CKD patients had sarcopenia, associated with age, low BMI, and impaired physical performance, aligning with current international recommendations for systematic screening in CKD.