SEIZURE CONTROL STATUS AND ASSOCIATED FACTORS IN EPILEPSY PATIENTS
Main Article Content
Abstract
Background: Epilepsy is a common chronic neurological disorder that significantly impacts health and quality of life. Although most patients can achieve seizure control with antiepileptic drugs, approximately one-third remain inadequately controlled. Objectives: To determine the rate of seizure control and identify associated factors among epilepsy patients treated at Can Tho Central General Hospital. Materials and Methods: A cross-sectional descriptive study was conducted on 41 patients aged ≥16 years diagnosed with epilepsy. Good seizure control was defined as being seizure-free during the previous three months. Results: Sociodemographic factors such as age, sex, residence, occupation, marital status, and comorbidities were not significantly associated with seizure control (p>0.05). In contrast, a pre-treatment seizure frequency of >3 seizures/month, disease duration of 1–5 years, and the presence of previous craniotomy findings on imaging were significantly associated with poorer seizure control (p<0.05). Conclusion: Most patients achieved good seizure control; however, high pre-treatment seizure frequency, longer disease duration, and structural brain abnormalities were associated with inadequate control. These factors should be carefully considered in clinical management and follow-up.
Article Details
Keywords
Epilepsy, seizure control, associated factors.
References
2. Hsu CH, Chen L, Su TC, Kuo HC, Lee YC, Hsieh CL, et al. Effect on satisfactory seizure control and heart rate variability of thread-embedding acupuncture for drug-resistant epilepsy: a patient-assessor blinded, randomized controlled trial. Medicine (Baltimore). 2023;102(37):e35175. https://doi: 10.1155/2023/5871991.
3. Song P, Liu Y, Yu X, Wu A, Zhou H, Shan S, et al. Prevalence of epilepsy in China: a systematic review and meta-analysis. Sci Rep. 2018;8(1):17567. https://doi: 10.7189/jogh.07.020706.
4. Nguyễn Văn Tuyên, Vương Thừa Đức. Đặc điểm dịch tễ học lâm sàng bệnh động kinh tại cộng đồng dân cư tỉnh Thái Bình. Tạp chí Y học Việt Nam. 2023;526(2). https://doi.org/10.51298/vmj.v520i1B.3872.
5. Kim DW, Lee SK, Yun CH, Kim KK, Lee SY, Park HK, et al., Clinical characteristics of patients with treated epilepsy in Korea: a nationwide epidemiologic study. Epilepsia. 2014;55(1):67-75. https://doi: 10.1111/epi.12469.
6. Scheffer IE, Berkovic S, Capovilla G, Connolly MB, French J, Guilhoto L, et al. ILAE classification of the epilepsies: Position paper of the ILAE Commission for Classification and Terminology. Epilepsia. 2017;58(4):512-521. https://doi:10.1111/epi.13709.
7. Phạm Hồng Đức, Vũ Anh Nhị. Tỷ lệ hiện mắc và khoảng trống điều trị động kinh tại nội thành, Thành phố Hồ Chí Minh. Tạp chí Y học Việt Nam. 2022;520(1B). https://doi.org/10.51298/vmj.v520i1B.3872.
8. Kahsay, G. G., Gidey, K., and Berha, A. B. (2025). Treatment outcomes, medication adherence and predictors among patients with epilepsy in Mekelle City Hospitals, Ethiopia: a multicentre observational cross-sectional study. BMJ open, 15(6), e097067. https://doi.org/10.1136/bmjopen-2024-097067.
9. Tian, N., Boring, M., Kobau, R., Zack, M. M., & Croft, J. B. (2018). Active Epilepsy and Seizure Control in Adults - United States, 2013 and 2015. MMWR. Morbidity and mortality weekly report, 67(15), 437-442. https://doi.org/10.15585/mmwr.mm6715a1.
10. My Sylaphet, Đỗ Thanh Hương, Đỗ Phương Thảo. Kết quả điều trị động kinh và một số yếu tố liên quan đến động kinh kháng thuốc ở trẻ em tại Bệnh viện Xanh Pôn. Tạp chí Y học Việt Nam. 2025;546(3). https://doi:10.51298/vmj.v546i3.12688.