EFFECTS OF VIETNAM GREEN COFFEE BEAN EXTRACT TO BLOOD PRESSURES IN EXPERIMENTAL ANIMALS

Lê Văn Quân1,, Cấn Văn Mão1, Nguyễn Trọng Nghĩa2, Nguyễn Văn Thuần3
1 Vietnam Military Medical University
2 108 Military Central Hospital
3 Medical Department, Staff, Military Region 4

Main Article Content

Abstract

Objective: To assess effects of Vietnam gree coffee bean extract to blood pressures in experimental animals. Subjects and methods: 40 Swiss mice were divided randomly into 4 groups: group 1 (control) – animals were administrated vehicle at 0,1ml/10g; groups 2, 3 and 4 (treatments) – animals were contributed green coffee bean extracts at doses 200mg/kg, 300mg/kg and 400mg/kg, respectively. Animals were contributed vehicle or green coffee bean extracts daily for 3 continous weeks. After then, animals were perfomed running tests in the treadmill system. Blood presures of all animals were measured before and after the test 1 minute, 3 minutes, 5 minutes. Results: All kinds of blood pressures in animals treated green coffee bean extracts at doses 400mg/kg and 300mg/kg were lower than these in control animals after the behavioral test. Conclusion: Vietnam green coffee bean extract induced stability of blood presures in experimental animals.

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References

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