STUDY RIGHT VENTRICULAR FUNCTION IN PATIENTS WITH AORTIC VALVE SEVERE STENOSIS

Đỗ Mạnh Hùng1,, Nguyễn Thị Hải Yến2, Nguyễn Thị Bạch Yến2
1 Bai Chay Hospital
2 Bach Mai Hospital

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Abstract

Aim: Study the rate of right ventricular dysfunction and the correlate between right ventricular function and some parameters assessing the stage of aortic valve stenosis and left ventricular function on echocardiography in patients with severe aortic valve stenosis. Subjects: Patient with aortic valve severe stenosis (According to the standards of the American Society of Echocardiography: peak velocity transaortic valve˃4m/s, AVA< 1cm2, mean aortic pressure gardient ˃40mmHg) came and treated at Tim Mach Quoc Gia hospital august 2020 to august 2021. Method: Prospective study, cross-sectional, choose convenient sample. Assessment right venticular function (TAPSE, FAC, S’, E/e’ lateral tricupid valve, RIMP, diameters of right venticular). Result: Forty-seven patients were studied by echocardiography. Incedence right ventricular global dysfunction assessment by Tei (˃0,54) is 68,1%, right ventricular systolic dysfunction (S’<9,5 cm/s) is 29,8%, (FAC<35%) is 4,3%. Right ventricular function measured by TAPSE was moderately correlated with maximal velocity through the aortic valve (r = 0.389, P <0,01). FAC, Tei measured by tissue doppler, S’ velocity were all correlate with index aortic valve area with correlation coefficient (r= 0,361; -0,297; 0,302 p<0,05) respectively. The longitudinal right ventricular diameter was moderately correlated with the maximal velocity across the aortic valve (r = 0.38 p < 0.01) and the aortic valve area measured by the continuous equation (r = 0.313 p <0.05), mean gradient pressure van (r=0,412 p< 0,01), max gradient pressure (r= 0,411 p<0,01). TAPSE, FAC, S’velocity, Tei were all strong corellate with left ventricular ejection fraction (EF) with correlation coefficient (r= 0,512; 0,658; -0,372; 0,409; p< 0,01). Conclusion: Right ventricular dysfunction is quite common in patients with aortic stenosis. Right ventricular function was correlated with peak systolic transaortic velocity (TAPSE), with aortic valve area index (FAC, S', Tissue Tei) and left ventricular systolic function.

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References

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