Article Sidebar

pdf
Date Published: 28/01/2026
Abstract Views: 61
Views pdf: 47
DOI: https://doi.org/10.51298/vmj.v558i1.16944
Issue
Vol. 558 No. 1 (2026)
Section
Các bài báo
How to Cite
Nguyễn, Đức H., Phạm, N. H., Trần, T. M. T., & Lâm, T. N. (2026). THE VALUE OF MAGNETIC RESONANCE IMAGING IN PREDICTING CERVICAL LYMPH NODE METASTASIS BASED ON TUMOR DEPTH OF INVASION AND IN T STAGING OF TONGUE CANCER. Vietnam Medical Journal, 558(1). https://doi.org/10.51298/vmj.v558i1.16944

THE VALUE OF MAGNETIC RESONANCE IMAGING IN PREDICTING CERVICAL LYMPH NODE METASTASIS BASED ON TUMOR DEPTH OF INVASION AND IN T STAGING OF TONGUE CANCER

Đức Hiếu Nguyễn, Ngọc Hoa Phạm, Thị Mai Thuỳ Trần, Thanh Ngọc Lâm

Main Article Content

Abstract

Objective: To determine the value of depth of invasion measured on magnetic resonance imaging in predicting malignant cervical lymph nodes and to evaluate the concordance between magnetic resonance imaging and histopathology in T staging of tongue cancer. Methods: A cross-sectional descriptive study was conducted on 47 patients diagnosed with squamous cell carcinoma of the anterior two-thirds of the tongue who underwent surgery at the University Medical Center Ho Chi Minh City from January 2021 to May 2025. Results: A strong correlation was found between the depth of invasion measured on magnetic resonance imaging and on histopathology (ρ = 0.828, p < 0.001). The rate of malignant nodes increased significantly with the level of radiological depth of invasion: 0% in the rDOI ≤ 5 mm group, 14.3% in the > 5-10 mm group, and 68.0% in the > 10 mm group (p < 0.001). The optimal rDOI cutoff for predicting malignant nodes was 10 mm, with a sensitivity of 89.5% and a specificity of 71.4% (AUC = 0.858). T staging on magnetic resonance imaging also showed good agreement with histopathology (Kappa coefficient = 0.772). Conclusion: MRI-measured depth of invasion is a reliable predictor for the risk of malignant cervical lymph nodes in patients with tongue cancer; additionally, MRI is also a highly valuable tool for T staging.

Article Details

Keywords

tongue cancer, magnetic resonance imaging, depth of invasion, malignant cervical lymph nodes, predictive factor, T staging.

References

Alharbi B., Alessa M., Alsayid H., et al. Magnetic resonance imaging accuracy in assessing depth of invasion in tongue squamous cell carcinomas and predicting cervical nodal metastasis. Eur Rev Med Pharmacol Sci. 2024;28(5):1783-1790.
2. Haraguchi K., Yoshiga D., Oda M., et al. Depth of invasion determined by magnetic resonance imaging in tongue cancer can be a predictor of cervical lymph node metastasis. Oral Surg Oral Med Oral Pathol Oral Radiol. 2021;131(2):231-240.
3. Jung J., Cho N. H., Kim J., et al. Significant invasion depth of early oral tongue cancer originated from the lateral border to predict regional metastases and prognosis. Int J Oral Maxillofac Surg. 2009;38(6):653-60.
4. Preda L., Chiesa F., Calabrese L., et al. Relationship between histologic thickness of tongue carcinoma and thickness estimated from preoperative MRI. Eur Radiol. 2006;16(10):2242-8.
5. Puri S. K., Fan C. Y., Hanna E. Significance of extracapsular lymph node metastases in patients with head and neck squamous cell carcinoma. Curr Opin Otolaryngol Head Neck Surg. 2003; 11(2):119-23.
6. Veiga-San Roman P., Villanueva San Vicente V., Rodriguez-Gonzalez M. A., et al. Survival among treated tongue cancer patients: a single-center experience. Discov Oncol. 2024;15(1):127.
7. Vidiri A., Panfili M., Boellis A., et al. The role of MRI-derived depth of invasion in staging oral tongue squamous cell carcinoma: inter-reader and radiological-pathological agreement. Acta Radiol. 2020;61(3):344-352.
8. Zwittag P., Asel C., Gabriel M., et al. MRI and PET/CT in the assessment of lymph node metastases in head and neck cancer. Sci Rep. 2023;13(1):19347.