Article Sidebar

pdf
Date Published: 28/01/2026
Abstract Views: 71
Views pdf: 48
DOI: https://doi.org/10.51298/vmj.v558i1.16955
Issue
Vol. 558 No. 1 (2026)
Section
Các bài báo
How to Cite
Đỗ, M. H. (2026). SUCCESSFUL ENDOSCOPIC SUBMUCOSAL DISSECTION FOR SYNCHRONOUS EARLY ESOPHAGEAL SCC: A CASE REPORT. Vietnam Medical Journal, 558(1). https://doi.org/10.51298/vmj.v558i1.16955

SUCCESSFUL ENDOSCOPIC SUBMUCOSAL DISSECTION FOR SYNCHRONOUS EARLY ESOPHAGEAL SCC: A CASE REPORT

Minh Hùng Đỗ

Main Article Content

Abstract

A 51-year-old man with a long history of heavy smoking (30 years) and chronic hepatitis B came to the hospital complaining of abdominal pain and bloating. Upper endoscopy revealed two suspicious esophageal lesions: one in the cervical segment and the other in the mid-thoracic segment, corresponding to JES classifications B1 and B2. Histological analysis of biopsy specimens confirmed moderately differentiated squamous cell carcinoma. Chest CT showed focal thickening of the esophageal wall but no signs of deep invasion or regional lymphadenopathy. The patient underwent en bloc endoscopic submucosal dissection (ESD) of both lesions in a single session without complications. Histopathology revealed high-grade intraepithelial neoplasia with negative margins. At 3, 6, 9 months, follow-up endoscopy showed well-healed scars with no recurrence. Additionally, two rectal neuroendocrine tumors were resected via ESD6. This case highlights the feasibility, safety, and efficacy of ESD in synchronous early esophageal SCC

Article Details

Keywords

esophageal squamous cell carcinoma; endoscopic submucosal dissection; synchronous cancer; neuroendocrine tumor; case report

References

1. Liu KS, Raza SA, El-Serag HB, Thrift AP. Trends in esophageal adenocarcinoma and esophageal squamous cell carcinoma incidence in the United States from 1992 to 2019. Cancers (Basel). 2022;14(24):6049. doi:10.3390/cancers 14246049.
2. Then EO, Lopez M, Saleem S, Gayam V, Sunkara T, et al. Esophageal cancer: an updated SEER database analysis. World J Oncol. 2020;11(2):55-64. doi:10.14740/wjon1254.
3. Lin YF, Lee JM, Lin MW, Huang PM, Chen KC, et al. Long-term survival outcome of patients with early esophageal cancer after ESD and esophagectomy. Dis Esophagus. 2020. Epub ahead of print. doi:10.1093/dote/doaa999.
4. Gong L, Yue J, Duan X, Jiang H, Zhang H, et al. Comparison of therapeutic effects of ESD and minimally invasive esophagectomy for T1 stage esophageal carcinoma. Thorac Cancer. 2019; 10(10):2161-2167.doi:10.1111/1759-7714.13194.
5. Wang CY, Chen BH, Lee CH, Le PH, Tsou YK, et al. cT1N0M0 esophageal squamous cell carcinoma invading muscularis mucosa or submucosa: results of ESD versus esophagectomy. Cancers (Basel). 2022;14(2):424. doi:10.3390/cancers14020424.
6. Lee HD, Chung H, Kwak Y, Choi J, Lee A, et al. Endoscopic submucosal dissection versus surgery for superficial esophageal squamous cell carcinoma: a propensity score-matched survival analysis. Clin Transl Gastroenterol. 2020;11(5): e00193. doi:10.14309/ctg.0000000000000193.
7. Liu W, Yu Z. Clinical characteristics and prognosis of synchronous multiple primary esophageal squamous cell carcinoma: a retrospective study. Dis Esophagus. 2024;37(Suppl 1): doae057.390. doi:10.1093/ dote/doae057.390.
8. Tsai PC, Ting YC, Hsu PK, Hung JJ, Huang CS, et al. Overall survival for esophageal SCC with multiple primary cancers after curative esophagectomy. Cancers (Basel). 2022;1 4(21):5263. doi:10.3390/ cancers14215263.
9. Xu Y, Zhao L, Shi A, Chen C, Cao J, et al. Radiotherapy improves survival in patients with lymphovascular invasion in pT1b esophageal squamous cell carcinoma after ESD. Am J Gastroenterol. 2023;118(8):1344-1352. doi:10.14309/ajg.0000000000002257.
10. Wang S, Chen X, Wang A. Lymph node metastasis pattern in thoracic superficial esophageal squamous cell carcinoma. Dis Esophagus. 2018;31(Suppl 1):93-94. doi:10.1093/dote/doy089.