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CLINICAL, DOPPLER, AND PERINATAL CHARACTERISTICS OF SEVERE LATE-ONSET FETAL GROWTH RESTRICTION: A RETROSPECTIVE DESCRIPTIVE STUDY
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Abstract
Objective: To describe the clinical characteristics, Doppler findings, and perinatal outcomes of pregnancies with severe late-onset fetal growth restriction (FGR). Materials and Methods: A retrospective descriptive study was conducted on 34 pregnancies diagnosed with severe late-onset FGR (EFW or AC < 3rd percentile) that were delivered at Tu Du Hospital between April 2022 and December 2022. Maternal characteristics, gestational age at diagnosis and delivery, fetal Doppler indices, and perinatal outcomes were analyzed using descriptive statistics. Results: Among 34 cases of severe late-onset FGR, 11 cases (32.4%) had adverse perinatal outcomes (APO). The mean gestational age at diagnosis and delivery were 37.4 ± 1.2 weeks and 37.6 ± 1.2 weeks, respectively. The mean birth weight was 2,332.4 ± 288.6 g. There were 5 cases (14.7%) with CPR < 5th percentile, 4 cases (11.8%) with UA-PI > 95th percentile, and 3 cases (8.8%) with MCA-PI < 5th percentile. Conclusions: Severe late-onset FGR carries a significant risk of adverse perinatal outcomes despite term gestation. Serial Doppler surveillance, especially severe EFW or AC, plays an important role in the early detection of fetal hemodynamic compromise and in determining the optimal timing of delivery to improve perinatal outcomes.
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Keywords
adverse perinatal outcomes; late-onset fetal growth restriction; severe fetal growth restriction.
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