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CLINICAL AND PARACLINICAL EPIDEMIOLOGICAL CHARACTERISTICS OF BACTERIAL DYSENTERY AT HAI PHONG CHILDREN'S HOSPITAL
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Abstract
Objective: The study aims to describe the clinical and paraclinical characteristics and antibiotic resistance of Shigella infection in children. Methods: A cross-sectional descriptive study was conducted on 38 pediatric patients with Shigella infection at Hai Phong Children's Hospital from August 2019 to July 2024. Results: The most affected age group was 2 months - 2 years old (52.6%), followed by 2 - 5 years old (34.2%). Boys accounted for 63.2%. The most common reasons for hospitalization were loose stools (42.1%), fever (21.1%) and bloody mucus diarrhea (18.4%). 71.1% of patients had fever, mainly mild and moderate fever. Stool culture results showed that S. flexneri (52.7%) and S. sonnei (34.2%) were the two main agents. Shigella was highly resistant to amoxicillin (93.3%), cotrimoxazole (90.9%) and nalidixic acid (75%), while it was susceptible to chloramphenicol (75%) and ciprofloxacin (66.7%). The S. flexneri strain had a higher resistance rate than S. sonnei. Conclusion: Shigella infection in children is most common in children under 5 years old, in which S. flexneri is the main agent. Requires regular monitoring and appropriate selection of effective antibiotics such as ciprofloxacin and chloramphenicol.
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Keywords
Shigella, children, clinical characteristics, antibiotic resistance, Vietnam
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