NGHIÊN CỨU GIÁ TRỊ TIÊN LƯỢNG CỦA THANG ĐIỂM PAASH VÀ CÁC YẾU TỐ NGUY CƠ LIÊN QUAN TỚI KẾT CỤC CHỨC NĂNG THẦN KINH XẤU Ở BỆNH NHÂN CHẢY MÁU DƯỚI NHỆN DO VỠ PHÌNH ĐỘNG MẠCH NÃO

Abstract

Objective: To analyze the relationship between the PAASH score and neurological function outcome (modified Rankin scale) a number of risk-factors in relation to an adverse neurologic function at 1 month in patients with subarachnoid hemorrhage due to rupture of cerebral aneurysm. Patients and methods: A prospective, decribre study of 71 patients diagnosed with subarachnoid hemorrhage due to rupture of cerebral aneurysm were treated at Viet Duc Hospital from August 2019 to August 2020. Results: PAASHscore has a positive relationship with mRS = 4-6 at the time of 1 month with OR = 4,423 (95% CI: 2,378-4,927) having statistical significance with p <0.001, OR gradually increasing from 2.24 to 52.0 in severe degree according to PAASH level II to IV with p <0.005; AUROC = 0.829 between PAASHscore and mRS = 4-6, cut-off point PAASHscore = 2.5 has a sensitivity of 72.9% and a specificity of 86.6%; WFNSscore has a positive correlation with mRS = 4-6 at 1 month with OR = 2.47 (95% CI: 1,899-3,231) statistically significant with p <0.001, at degrees IV and V according to WFNSscore for OR = 12,256 and 71,0 (p <0.001); AUROC = 0.821 between WFNSscore and mRS = 4-6, the cut-off point WFNSscore = 3.5 had a sensitivity of 78% and a specificity of 79.5%. Conclusion: The PAASH scale is of good value in predicting functional outcomes 1 month after onset of patients with cerebral aneurysm rupture and is equivalent to the WFNS score.