FACTORS ASSOCIATED WITH TREATMENT OUTCOMES OF ESOPHAGEAL AND GASTRIC SUBMUCOSAL TUMORS USING THE SUBMUCOSAL TUNNELING ENDOSCOPIC RESECTION (STER) TECHNIQUE WITH FLEXIBLE ENDOSCOPY
Main Article Content
Abstract
Background: Submucosal Tunneling Endoscopic Resection (STER) is an advanced technique for the treatment of submucosal tumors (SMTs). Objective: To analyze factors associated with the treatment outcomes of esophageal and gastric submucosal tumors (SMTs) using Submucosal Tunneling Endoscopic Resection (STER). Methods: A prospective and retrospective study was conducted on 69 patients with submucosal tumors < 3 cm in diameter, performed at Can Tho University of Medicine and Pharmacy Hospital from October 2022 to February 2025. Results: The mean procedure time was 65.72 ± 46.81 minutes. Statistical analysis showed that tumor size was a significant factor affecting procedure time; the group with tumors ≥ 20 mm had significantly longer procedure times compared to the smaller tumor group (p=0.005). The complete resection rate reached 98.6%; however, no significant association was found between imaging characteristics (location, peritumoral vessels, growth pattern) and the complete resection rate (p > 0.05). Regarding recovery, full-thickness resection was identified as the only factor increasing the rate of postoperative pain at 24 hours (p=0.014). Conclusion: Tumor size is an important prognostic factor for the duration of the STER procedure. Preserving the serosal layer significantly helps reduce postoperative pain.
Article Details
Keywords
Submucosal tumor, submucosal tunneling endoscopic resection, STER.
References
2. Liu, H., Ma, Q., & Zhu, L. (2025). The efficacy and safety of submucosal tunnel endoscopic resection for the treatment of upper gastrointestinal submucosal tumors: a systematic review and meta-analysis. Frontiers in Oncology, 15, 1584205.
3. Tun, K. M., Dhindsa, B. S., Dossaji, Z., Deliwala, S. S., Narra, G., Haque, L., ... & Adler, D. G. (2023). Efficacy and safety of submucosal tunneling endoscopic resection for subepithelial tumors in the upper GI tract: a systematic review and meta-analysis of> 2900 patients. iGIE, 2(4), 529-537.
4. Wang H, Feng X, Ye S, et al. (2016). A comparison of the efficacy and safety of endoscopic full-thickness resection and laparoscopic-assisted surgery for small gastrointestinal stromal tumors. Surg Endosc, 30:3357-61.
5. Wani S., Muthusamy V.R., and Komanduri S. (2014), "EUS-guided tissue acquisition: an evidence-based approach (with videos)", Gastrointest Endosc, 80(6), pp. 939-959 e937
6. Xu MD, Cai MY, Zhou PH, et al. (2012). Submucosal tunneling endoscopic resection: a new technique for treating upper Gl submucosal tumors originating from the muscularis propria layer (with videos). Gastrointest Endosc, 75: 195-9.
7. Ye Li-Ping, Zhang Yu, Yuo Li-Ping, et al. (2016). Safety of endoscopic resection for upper gastrointestinal subepithelial tumors originating from the muscularis propria layer: an analysis of 733 tumors. Am J Gastroenterol, 111:788-96.