DISORDER OF IRON METABOLISM IN PATIENTS WITH HELICOBACTER PYLORI INFECTION

Huỳnh Phương Duy1, Lâm Vĩnh Niên1, Đoàn Thanh Hải1, Hà Mạnh Tuấn1,
1 University of Medicine and Pharmacy at Ho Chi Minh City

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Abstract

Background: The percentage of patients have a Iron metabolism disorders with Helicobacter pylori changes about iron serum, specially the ratio of iron is about deficiency 35%. Objective: Determine the correlation between iron deficiency status in patients diagnosed with Helicobacter pylori infection. Methods: case-control study. Results: Serum iron in the group of patients positive for H.pylori is lower than in the negative group (59,4 ± 3,92 μg/dL và 82,3 ± 3,04 μg/dL, p<0,001). HP-positive patients have a 10.6 times higher rate of serum iron reduction (OR= 10,6; KTC95% 5,3 – 22,3) compared with those who were negative for HP, with p<0,001. The serum iron level has a relationship with red blood cell indices including Hb (r=0,24, p<0,001), MCV (r=0,28, p<0,001), MCH (r=0,21, p<0,001). Conclusion: There is a relationship between Helicobacter pylori infection and disorder of iron metabolism in patients positive with HP.

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References

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