CORRELATION OF HISTOPATHOLOGY AND LARYNGOSCOPIC FEATURES IN VOCAL FOLD LESIONS
Main Article Content
Abstract
Objectives: To investigate the laryngoscopic and histopathological features, and to analyze the associations between clinical characteristics, laryngoscopic findings, and histopathological diagnoses of vocal fold lesions. Materials and methods: A retrospective cross-sectional study was conducted on 202 patients with vocal cord lesions who underwent laryngoscopic examination and biopsy at the University Medical Center Ho Chi Minh City from January 2023 to December 2023. Results: The mean age was 55.1 ± 12.0 years (range: 22–94), with a predominance of males (91.6%). Benign lesions and low-grade dysplasia accounted for 78.2%, while high-grade dysplasia and squamous cell carcinoma represented 21.8%. Laryngoscopic features such as leukoplakia, exophytic masses, and ulcerations were significantly associated with high-grade/malignant lesions (p < 0.05). Conclusions: Laryngoscopic examination provides useful initial guidance in the evaluation of vocal cord lesions; however, histopathology remains the gold standard for definitive diagnosis. The combination of both methods is crucial to enhance diagnostic accuracy in clinical practice.
Article Details
Keywords
Vocal cord, laryngoscopy, histopathology, dysplasia, squamous cell carcinoma.
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