CORRELATION BETWEEN LUNG-RADS CLASSIFICATION AND HISTOPATHOLOGICAL RESULTS IN PATIENTS WITH SOLITARY PULMONARY NODULES DETECTED ON CHEST COMPUTED TOMOGRAPHY
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Abstract
Objective: To describe the imaging characteristics of solitary pulmonary nodules and to assess the agreement between Lung-RADS classification and histopathology. Methods: A cross-sectional descriptive study was conducted on 52 patients with solitary pulmonary nodules detected on Chest CT, all of whom underwent histopathological confirmation. Results: Solitary pulmonary nodules were most commonly located in the right upper lobe (42,3%). Solid nodules accounted for 90,4%, while part solid nodules accounted for 9,6%. The mean size of the nodules was 20.4± 5.4mm. All nodules were classified as Lung-RADS 4, with the 4X subcategory being the most common (59,6%). Malignant lesions were more common than benign (82,7% vs 17,3%). Adenocarcinoma accounted for the highest proportion among malignant lesions (73,1%). The probability of malignancy of pulmonary nodules increased progressively with Lung-RADS category. Lung-RADS 4X nodules had a 29-fold higher odds of malignancy compared with Lung-RADS 4A (p < 0.05), whereas Lung-RADS 4B nodules had an 8-fold increased odds of malignancy compared with Lung-RADS 4A, a difference that did not reach statistical significance (p >0.05). Conclusion: Lung-RADS classification has a reasonable ability to predict histopathological outcomes in patients with solitary pulmonary nodules
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Keywords
chest computed tomography, solitary pulmonary nodules, Lung-RADS
References
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