CORRELATION BETWEEN LUNG-RADS CLASSIFICATION AND HISTOPATHOLOGICAL RESULTS IN PATIENTS WITH SOLITARY PULMONARY NODULES DETECTED ON CHEST COMPUTED TOMOGRAPHY

Thị Quỳnh Hà, Duy Dũng Lê, Phong Thu Lê, Phan Ninh Trần, Thị Thu Hằng Tống, Minh Chi Phạm

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Abstract

Objective: To describe the imaging characteristics of solitary pulmonary nodules and to assess the agreement between Lung-RADS classification and histopathology. Methods: A cross-sectional descriptive study was conducted on 52 patients with solitary pulmonary nodules detected on Chest CT, all of whom underwent histopathological confirmation. Results: Solitary pulmonary nodules were most commonly located in the right upper lobe (42,3%). Solid nodules accounted for 90,4%, while part solid nodules accounted for 9,6%. The mean size of the nodules was 20.4± 5.4mm. All nodules were classified as Lung-RADS 4, with the 4X subcategory being the most common (59,6%). Malignant lesions were more common than benign (82,7% vs 17,3%). Adenocarcinoma accounted for the highest proportion among malignant lesions (73,1%). The probability of malignancy of pulmonary nodules increased progressively with Lung-RADS category. Lung-RADS 4X nodules had a 29-fold higher odds of malignancy compared with Lung-RADS 4A (p < 0.05), whereas Lung-RADS 4B nodules had an 8-fold increased odds of malignancy compared with Lung-RADS 4A, a difference that did not reach statistical significance (p >0.05). Conclusion: Lung-RADS classification has a reasonable ability to predict histopathological outcomes in patients with solitary pulmonary nodules

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References

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