EVALUATION OF EARLY EFFICACY OF ENDOVASCULAR INTERVENTION IN THE TREATMENT OF BENIGN PROSTATIC HYPERPLASIA
Main Article Content
Abstract
Objective: To evaluate the early efficacy of prostatic artery embolization (PAE) in the treatment of benign prostatic hyperplasia (BPH). Subject and Methods: A descriptive case series study was conducted on 47 patients diagnosed with BPH who underwent PAE at Tam Anh General Hospital, Ho Chi Minh City, from September 2022 to August 2024. Treatment efficacy was assessed based on changes in the International Prostate Symptom Score (IPSS), quality of life (QoL) score, prostate volume, post-void residual urine volume (PVR), and clinical response at 3 and 6 months post-intervention. Results: The mean IPSS before intervention was 28.4 ± 2.9; it decreased by 51.1% at 3 months and by 53.5% at 6 months post-intervention. The mean QoL score was 4.6 ± 0.6 before intervention, with a reduction of 39.1% at 3 months and 43.5% at 6 months. The average prostate volume was 78.6 ± 28.5 mL before intervention, decreasing by 23.9% at 3 months and by 37.5% at 6 months. The mean PVR was 75 ± 82.0 mL before intervention, with a reduction of 42.4% at 3 months and 69.8% at 6 months. The overall clinical response rate at both 3 and 6 months was 87.2%. The rate of minor complications was 17%, with urinary tract infections accounting for 12.8%. Conclusion: Prostatic artery embolization is a minimally invasive, safe, and effective treatment modality that significantly improves lower urinary tract symptoms and quality of life in patients with benign prostatic hyperplasia.
Article Details
Keywords
Benign prostatic hyperplasia (PBH), prostatic artery embolization (PAE), IPSS: International Prostate Symptom Score, QoL: Quality of Life, prostate volume, post-void residual urine volume (PVR).
References
2. Pisco JM, Rio Tinto H, Campos Pinheiro L, et al. Embolisation of prostatic arteries as treatment of moderate to severe lower urinary symptoms (LUTS) secondary to benign hyperplasia: results of short- and mid-term follow-up. Eur Radiol. Sep 2013; 23(9):2561-72. doi:10.1007/s00330-012-2714-9
3. Sapoval M, Thiounn N, Descazeaud A, et al. Prostatic artery embolisation versus medical treatment in patients with benign prostatic hyperplasia (PARTEM): a randomised, multicentre, open-label, phase 3, superiority trial. Lancet Reg Health Eur. Aug 2023;31:100672. doi:10.1016/j.lanepe.2023.100672
4. Bilhim T, Pisco J, Pereira JA, et al. Predictors of Clinical Outcome after Prostate Artery Embolization with Spherical and Nonspherical Polyvinyl Alcohol Particles in Patients with Benign Prostatic Hyperplasia. Radiology. Oct 2016; 281(1):289-300. doi:10.1148/radiol.2016152292
5. Vũ Đăng Dũng, Ngô Tuấn Minh, Nguyễn Việt Dũng, Nguyễn Xuân Khái, Lê Thanh Dũng. Nghiên cứu kết quả sớm điều trị tăng sản lành tính tuyến tiền liệt bằng phương pháp nút động mạch tiền liệt tuyến. Tạp chí Y học Việt Nam. 2021;504(2)doi:10.51298/vmj.v504i2.928
6. Trịnh Tú Tâm, Nguyễn Quốc Dũng, Nguyễn Xuân Hiền. Nút động mạch tuyến tiền liệt điều trị tăng sinh lành tính tuyến tiền liệt: Kết quả điều trị sau 6 tháng và 12 tháng. Tạp chí y dược lâm sàng 108. 2021;16(4)doi:10.52389/ydls.v16i4.777
7. Delazar S, Azadnajafabad S, Firouznia K, Nowroozi MR, Amini E, Fotouhi M, Ghanaati H. Outcomes of Prostatic Artery Embolization for Treating Benign Prostatic Hyperplasia Symptoms: A Prospective Single-Center Study. Health Sci Rep. Mar 2025;8(3):e70565. doi:10.1002/ hsr2.70565
8. Pisco JM, Bilhim T, Pinheiro LC, et al. Medium- and Long-Term Outcome of Prostate Artery Embolization for Patients with Benign Prostatic Hyperplasia: Results in 630 Patients. J Vasc Interv Radiol. Aug 2016;27(8):1115-22. doi:10.1016/j.jvir.2016.04.001
9. Noha E, Osama H, Hussein A, Allam A. Prostatic artery embolization in treatment of benign prostatic hyperplasia: outcome and efficacy in medium-sized compared to large prostates. The Egyptian Journal of Radiology and Nuclear Medicine. 2025;56(1)doi:10.1186/s43055-025-01497-y
10. Meira M, de Assis AM, Moreira AM, Antunes AA, Carnevale FC, Srougi M. Intravesical Prostatic Protrusion Does Not Influence the Efficacy of Prostatic Artery Embolization. J Vasc Interv Radiol. Jan 2021;32(1):106-112. doi:10. 1016/j.jvir.2020.09.023