SINH THIẾT VI VÔI HOÁ TUYẾN VÚ DƯỚI HƯỚNG DẪN SIÊU ÂM: HIỆU QUẢ VÀ ỨNG DỤNG

Abstract

Objective: To evaluate the effectiveness of ultrasound-guided core needle biopsy for breast microcalcifications, identify factors associated with the retrieval of calcified tissue, and assess its clinical utility in breast cancer diagnosis. Subject and Methods: A cross-sectional descriptive study was conducted on 71 patients with breast microcalcifications visible on ultrasound, who underwent ultrasound-guided core needle biopsy at K Hospital, Tan Trieu campus. Clinical, imaging, and biopsy-related variables were collected. Statistical analysis included Chi-square test, univariate and multivariate logistic regression to determine factors associated with successful retrieval of calcified tissue. Results: The technical success rate was 80.3%, with most lesions diagnosed as malignant (78.9%). Independent predictive factors included calcification cluster size >1 cm (OR = 4.13; 95% CI: 1.23–13.84), BI-RADS 5 classification (OR = 5.75; 95% CI: 1.28–25.76), and higher number of core samples (OR = 1.97; 95% CI: 1.08–3.61). Most patients experienced no complications (77.4%); minor complications included bruising, mild bleeding, and transient infection, with no serious adverse events. Conclusion: Ultrasound-guided core needle biopsy for breast microcalcifications is a feasible, safe, and highly diagnostic technique in clinical practice, especially suitable for facilities without stereotactic guidance systems. Selecting lesions with larger calcification clusters, higher BI-RADS categories, and obtaining more tissue samples may improve technical success rates.