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Date Published: 02/02/2026
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DOI: https://doi.org/10.51298/vmj.v558i2.17085
Issue
Vol. 558 No. 2 (2026)
Section
Các bài báo
How to Cite
Khổng, T. T., Hoàng, T. H., Nguyễn, V. L., & Đào, H. N. (2026). CLINICAL AND PARACLINICAL CHARACTERISTICS OF HUMAN HERPESVIRUS 6 INFECTION IN CHILDREN AT THE VIETNAM NATIONAL CHILDREN’S HOSPITAL 2020–2025. Vietnam Medical Journal, 558(2). https://doi.org/10.51298/vmj.v558i2.17085

CLINICAL AND PARACLINICAL CHARACTERISTICS OF HUMAN HERPESVIRUS 6 INFECTION IN CHILDREN AT THE VIETNAM NATIONAL CHILDREN’S HOSPITAL 2020–2025

Thị Thư Khổng, Thị Huế Hoàng, Văn Lâm Nguyễn, Hữu Nam Đào

Main Article Content

Abstract

Objective: To describe clinical and paraclinical characteristics of HHV-6 infection in children at the National Children’s Hospital. Methods: A descriptive study combining retrospective and prospective on 76 patients under 16 years with confirmed HHV-6 by PCR in blood/CSF during 2020–2025. Results: Median age was 13 months, mostly <24 months. Fever (92.1%) and rash (53.9%) were most common; respiratory (35.5%), hepatic (27.6%), and neurological (23.7%) manifestations were notable. By age, roseola predominated <24 months; hepatic and rash in 24 months–<5 years; hepatic (62.5%), neurological (50.0%), multi-organ failure (37.5%) in ≥5 years. Subclinical findings: neutrophilia (60.5%), anemia (42.1%), thrombocytopenia (28.9%). Conclusions: HHV-6 mainly affects children <2 years with age-dependent patterns. Careful monitoring is essential for early recognition and management of complications.

Article Details

Keywords

Human herpesvirus 6; children; clinical features; subclinical findings.

References

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