MỘT SỐ YẾU TỐ LIÊN QUAN BIẾN CHỨNG SUY THƯỢNG THẬN DO GLUCOCORTICOIDS TRÊN BỆNH NHÂN GOUT TẠI BỆNH VIỆN ĐA KHOA HẢI DƯƠNG

Abstract

Objective: To analyze some factors related actors to the complications of adrenal insufficiency caused by the use of glucocorticoids in gout patients. Method: Cross-sectional descriptive study design. Including 102 eligible patients. Convenient sampling method. Results: High-dose glucocorticoids were used most in the patient group, accounting for 46.1%. Using GCs with a daily dose of > 7.5 mg prednisolone, for a period of ≥ 1 month, causes adrenal insufficiency with more symptoms and is more likely to cause hyponatremia than using the drug with a daily dose of ≤ 7.5 mg, for a period of < 1 month. Using glucocorticoids systemically also causes adrenal insufficiency with more symptoms and is more likely to cause hyponatremia than using the topical route. Conclusion: Gout is a specialized disease, with many risk factors for adrenal insufficiency if Glucocorticoids are prescribed. Therefore, the disease must be well managed so that patients can live with the disease for a long time, reduce side effects of treatment drugs, minimize complications, and improve their quality of life