CLINICAL AND PARA-CLINICAL CHARACTERISTICS OF MOTHERS GIVING BIRTH TO INFANTS WEIGHING 4000 GRAMS OR MORE AT HANOI OBSTETRICS AND GYNECOLOGY HOSPITAL DURING 2024–2025
Main Article Content
Abstract
Objective: To describe the clinical and para-clinical characteristics of mothers giving birth to infants weighing 4000 grams or more at Hanoi Obstetrics and Gynecology Hospital during the period 2024–2025. Subjects and Methods: A retrospective cross-sectional descriptive study was conducted on 94 cases of mothers whose newborns weighed ≥4000g immediately after birth at Hanoi Obstetrics and Gynecology Hospital from January 1, 2024, to March 31, 2025. Results: The average maternal age was 30.8 ± 4.6 years, with an average height of 159 cm. Maternal weight ranged from 55 to 119 kg. Primiparous women accounted for 30%, while multiparous women made up 70% (second birth: 40%, third: 21%, fourth: 8%, fifth: 1%). The rate of pre-pregnancy maternal comorbidities was 17% (16 out of 94 cases), including diabetes mellitus, cardiovascular diseases, thalassemia, hepatitis B, and thyroid disorders. Obstetric complications included 31% gestational diabetes mellitus (GDM) and 3% hypertensive disorders. The average birth weight was higher than the estimated weight from ultrasound, with a mean discrepancy of 295 grams. Full-term pregnancies (38–40 weeks) accounted for 93.6% (88 out of 94 cases), while preterm and post-term births made up 6.4% (6 out of 94 cases). Among the newborns, 64.9% were male and 35.1% female. The highest birth weight recorded was 4600g for male infants and 5000g for female infants. The average birth weight was 4131.4 ± 177.2 grams. Conclusion: Among mothers giving birth to infants over 4000 grams, gestational diabetes mellitus was the most prevalent obstetric condition (31%). Ultrasound can relatively accurately predict fetal weight, with an average error of 295 grams. Male fetal sex may be associated with birth weight exceeding 4000 grams.
Article Details
Keywords
Study subjects, diabetes mellitus, gestational diabetes mellitus, hypertension, preeclampsia
References
2. Tổng cục dân số - kế hoạch hóa gia đình. Vấn đề dân số hôm nay: Mức sinh ở Việt Nam - Tìm trên Google. Accessed October 16, 2025.
3. Nghiên cứu tình hình trẻ sơ sinh thừa cân tại khoa phụ sản Bệnh viện Trung Ương Huế | Tạp chí Phụ sản. Accessed October 16, 2025. https://vjog.vn/journal/article/view/424
4. Usta A, Usta CS, Yildiz A, et al. Frequency of fetal macrosomia and the associated risk factors in pregnancies without gestational diabetes mellitus. Pan Afr Med J. 2017;26:62. doi:10.11604/pamj.2017.26.62.11440
5. Hà Thị Thanh Nga. Nghiên cứu một số liên quan và kết quả xử trí thai to. Luận văn Thạc sỹ Y học. Trường Đại học Y Dược Huế; 2018.
6. Li Y, Liu QF, Zhang D, et al. Weight gain in pregnancy, maternal age and gestational age in relation to fetal macrosomia. Clin Nutr Res. 2015;4(2):104-109. doi:10.7762/cnr.2015.4.2.104
7. Risk factors for recurrent macrosomia and child outcomes - PubMed. Accessed October 16, 2025. https://pubmed.ncbi.nlm.nih.gov/ 30993581/
8. Stotland NE, Caughey AB, Breed EM, Escobar GJ. Risk factors and obstetric complications associated with macrosomia. Int J Gynaecol Obstet Off Organ Int Fed Gynaecol Obstet. 2004;87(3):220-226. doi:10.1016/j.ijgo. 2004.08.010
9. Macrosomia - StatPearls - Kệ sách NCBI. Accessed October 16, 2025.
10. Milner J, Arezina J. The accuracy of ultrasound estimation of fetal weight in comparison to birth weight: A systematic review. Ultrasound Leeds Engl. 2018;26(1):32-41. doi:10.1177/ 1742271X17732807