TỶ LỆ VÀ YẾU TỐ NGUY CƠ CỦA HỘI CHỨNG TIM THẬN TYPE 1 Ở BỆNH NHÂN SUY TIM CẤP

Abstract

Background: Cardiorenal syndrome type 1 (CRS type 1) is the development of acute kidney injury in patients with acute heart failure, contributing to increased mortality and prolonged hospitalization. Early identification of CRS type 1 is crucial, as it is closely associated with therapeutic prognosis and clinical outcomes. Therefore, determining the risk factors associated with CRS type 1 remains an important clinical priority. Objective: The aim of this study was to determine the prevalence and risk factors of CRS type 1 in patients admitted for acute heart failure. Methods: A descriptive cross-sectional study was conducted on 160 patients with acute heart failure admitted to 115 People’s Hospital from February 2025 to September 2025. Patients were categorized into two groups: those with and without CRS type 1. Demographic, comorbidity, and treatment-related characteristics were recorded. Risk factors for CRS type 1 were identified using multivariable logistic regression analysis. Results: Among 160 patients with acute heart failure, the prevalence of CRS type 1 was 31,3%. The mean age was 63,0 ± 14,6 years, with 85% aged above 50 years. Patients in group CRS type 1 exhibited a higher prevalence of comorbidities (hypertension, diabetes mellitus, and chronic kidney disease) and more severe clinical presentation at admission (NYHA class, heart rate,…) compared with group without CRS type 1. In multivariable logistic regression, NYHA class IV (OR = 66,623; 95% CI: 2,427 – 1828,776; p = 0,013), NT – proBNP > 8352 pg/mL (OR = 14,581; 95% CI: 1,039 – 204,570; p = 0,047), and in – hospital use of ACEi/ARB (OR = 0,029; 95% CI: 0,001 – 0,585; p = 0,021) were independently associated with CRS type 1. Conclusions: Acute kidney injury is a common consequence in patients with acute heart failure. Risk factors for CRS type 1 include NYHA class IV dyspnea, NT – proBNP levels > 8352 pg/mL, and the absence of ACEi/ARB therapy during hospitalization.