SEVERITY OF CORONARY ARTERY LESIONS ASSESSED BY GENSINI SCORE AND ASSOCIATED FACTORS IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION IN CAN THO

Văn Phát Ong, Hoàn Toàn Ngô, Thị Ngọc Nga Phạm, Thanh Phong Phạm, Viết An Trần

Main Article Content

Abstract

Background: Assessment of coronary artery lesion severity plays a crucial role in the prognosis and treatment strategy for patients with acute myocardial infarction. Objective: To determine the severity of coronary artery lesions using the Gensini score and identify associated factors in patients with acute myocardial infarction in Can Tho. Materials and methods: A cross-sectional descriptive study was conducted on 152 patients diagnosed with acute myocardial infarction who underwent coronary angiography. Lesion severity was quantified using the Gensini score. Results: Males accounted for 69.7% of the study population, and the elderly (≥ 60 years) comprised 72.4%. Hypertension was the most common risk factor (77.0%), and the hypertensive group had a significantly higher mean Gensini score compared to the non-hypertensive group (p=0.020). The mean Gensini score in the ST-segment elevation myocardial infarction (STEMI) group was significantly higher than in the non-ST-segment elevation myocardial infarction (NSTEMI) group (53.53 ± 26.74 vs. 27.34 ± 21.09; p<0.001). Multivariate regression analysis identified STEMI as the sole independent prognostic factor associated with an increased Gensini score (p<0.001). Age, gender, BMI, diabetes mellitus, dyslipidemia, and Killip class showed no statistically significant association in the multivariate model. Conclusions: Patients with ST-segment elevation myocardial infarction exhibit a heavier burden of coronary atherosclerosis. The clinical type of infarction is the most significant independent predictor of the Gensini score.

Article Details

References

Trần Hòa, Nguyễn Vinh Trung, Nguyễn Hồng Hà và cộng sự (2025), Nghiên cứu đặc điểm tổn thương động mạch vành và giá trị của nồng độ NT-proBNP, hs-CRP trong tiên lượng mức độ nặng của tổn thương động mạch vành ở bệnh nhân cao tuổi có hội chứng động mạch vành cấp không ST chênh lên, Tạp chí Y học Việt Nam, 2025;550(2). doi:10.51298/vmj.v550i2.14204
2. Aksu, F., & Ahmed, S. A. (2024). Gensini Score's Severity and Its Relationship with Risk Factors for Coronary Artery Disease Among Patients Who Underwent Angiography in Somalia's Largest PCI Centre. International journal of general medicine, 17, 187–192. https://doi.org/10.2147/IJGM.S384626
3. Charach, Lior, et al. "Using the Gensini score to estimate severity of STEMI, NSTEMI, unstable angina, and anginal syndrome." Medicine 100.41 (2021): e27331.
4. Duy Cong Tran, Linh Hoang Gia Le, Truc Thanh Thai, Sy Van Hoang, Minh Duc Do, Binh Quang Truong. "Association between ACE I/D genetic polymorphism and the severity of coronary artery disease in Vietnamese patients with acute myocardial infarction." Frontiers in Cardiovascular Medicine 10 (2023): 1091612.
5. Hao Thai Phan, Mai Thi Tuyet Ho. (2025). Value of lipoprotein (a) in predicting severity of coronary artery stenosis in patients with chronic coronary artery disease: a cross-sectional study in Vietnam. Frontiers in Cardiovascular Medicine, 12, 1669234.
6. Tanaka T, Miki K, Akahori H, et al. Comparison of coronary atherosclerotic disease burden between ST-elevation myocardial infarction and non-ST-elevation myocardial infarction: Non-culprit Gensini score and non-culprit SYNTAX score. Clin Cardiol. 2021;44(2): 238-243. doi:10.1002/clc.23534