ĐẶC ĐIỂM CẬN LÂM SÀNG CỦA BỆNH NHÂN VẢY NẾN VÀ VIÊM DA CƠ ĐỊA Ở VIỆT NAM

Abstract

Background: Dyslipidemia is increasingly recognized in psoriasis and atopic dermatitis due to systemic inflammation and cardiovascular risks. However, differences in lipid profiles between the two diseases remain inconsistent in previous reports. Objective: To compare serum lipid characteristics between patients with psoriasis and atopic dermatitis. Materials and Methods: A cross-sectional study was conducted at Ho Chi Minh City Dermatology Hospital from February to October 2025. Total cholesterol and high-density lipoprotein (HDL) levels were collected and statistically compared between groups. Results: Dyslipidemia was observed in both groups. Total cholesterol levels did not differ significantly between psoriasis and atopic dermatitis (p>0.05). In contrast, HDL levels were significantly lower in the atopic dermatitis group (p<0.001), indicating more prominent lipid metabolic alterations. The proportions of elevated total cholesterol and reduced HDL did not show significant differences. Conclusion: Dyslipidemia is present in both chronic inflammatory skin diseases. HDL appears to be a more sensitive clinical indicator than total cholesterol in differentiating metabolic disturbances. Monitoring cardiovascular risk may be particularly relevant in patients with atopic dermatitis.