RESULTS OF CONTINUOUS RENAL REPLACEMENT THERAPY IN THE TREATMENT OF SEPTIC SHOCK AT THE INTENSIVE CARE UNIT, THAI NGUYEN CENTRAL HOSPITAL
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Abstract
Objective: To describe the clinical and subclinical efficacy and outcomes of continuous hemodialysis in patients with septic shock. Methods: Patients diagnosed with septic shock were treated with continuous renal replacement therapy (CRRT) at the ICU, Thai Nguyen Central Hospital, from July 2024 to July 2025. Results: 40 patients, 27 males, 13 females, the mean age 62.3 ± 14.7 years. Respiratory tract infections accounted for the largest proportion of septic shock cases (55%). Before dialysis, the average number of organ failures 4.3 ± 1.00, SOFA score 11.9 ± 2.7.The severity before dialysis, organs failure 4.3 ± 1.00, SOFA score 11.9 ± 2.7. In the study, 14 patients (35%) achieved shock resolution, while 26 patients (65%) died. The average time to shock resolution was 88 ± 47.30 hours. Patients with pre-dialysis SOFA scores between 2 - 9 had a higher rate of shock resolution. Conclusion: Continuous renal replacement therapy is effective in the treatment of septic shock. Early initiation of therapy should be considered in patients diagnosed with septic shock.
Article Details
Keywords
Septic shock, Continuous renal replacement therapy (CRRT)
References
2. Martin G.S. (2012), “Sepsis, severe sepsis and septic shock: changes in incidence, pathogens and outcomes”, Expert Review of Anti-infective Therapy, 10, tr. 701–706.
3. Nguyễn Đức Phúc và cộng sự (2022), “Đánh giá hiệu quả của lọc máu liên tục trong điều trị suy đa tạng do sốc nhiễm khuẩn tại khoa Hồi sức tích cực Bệnh viện Hữu nghị Đa khoa Nghệ An”, Tạp chí Y học Việt Nam, 515, tr. 45–52.
4. Phạm Thị Ngọc Thảo và cộng sự (2012), “Đánh giá hiệu quả điều trị của kỹ thuật thay thế thận liên tục trong sốc nhiễm trùng”, Tạp chí Y học Thành phố Hồ Chí Minh, 16, tr. 145–150
5. Nguyễn Minh Lực và cộng sự (2020), “Đánh giá hiệu quả lọc máu liên tục bằng màng lọc oXiris trong phối hợp điều trị sốc nhiễm khuẩn”, Luận văn Bác sĩ nội trú, Trường Đại học Y Hà Nội.
6. DeForge L.E., Remick D.G. (1991), “Kinetics of TNF, IL-6, and IL-8 gene expression in LPS-stimulated human whole blood”, Biochemical and Biophysical Research Communications, 174, tr. 18–24.