TỶ LỆ TỬ VONG NỘI VIỆN VÀ CÁC YẾU TỐ LIÊN QUAN Ở BỆNH NHÂN CAO TUỔI MẮC VIÊM PHỔI CỘNG ĐỒNG

Abstract

Background: Community-acquired pneumonia (CAP) is one of the most common infectious diseases and causes a significant mortality rate. The incidence of community-acquired pneumonia is increasing among the elderly, with higher hospitalization and in-hospital mortality rates compared to other diseases. Objective: To determine the in-hospital mortality rate and describe the associated factors among elderly patients hospitalized with community-acquired pneumonia. Methods: A cross-sectional study was conducted on 293 inpatients aged ≥ 60 years, diagnosed with community-acquired pneumonia and treated at the Respiratory Department of Thong Nhat Hospital from March to September 2023. Multivariate logistic regression was used to identify factors independent associated with in-hospital mortality. A p-value of < 0.05 was considered statistically significant. Results: There were 293 patients participating in the study, the in-hospital mortality rate was 11.9%. The study found that those who died had higher age, clinical frailty (CFS), Charlson Comorbidity Index (CCI), blood urea, C-Reactive Protein (CRP) and Pneumonia Severity Assessment Score (CURB-65) than those who were discharged. In contrast, patients who died had lower Mini Nutritional Assessment (MNA-SF) scores. Through multivariate analysis, pre-hospital frailty (CFS) (OR = 2.17), MNA-SF (OR = 0.77) and CURB-65 (OR = 3.71) were independently associated with in-hospital mortality in elderly patients hospitalized with community-acquired pneumonia. Conclusion: The in-hospital mortality rate among elderly patients with community-acquired pneumonia was relatively moderate. Pre-admission frailty CFS and pneumonia severity CURB-65 were significant predictors of in-hospital death. These findings underscore the importance of comprehensive assessments of frailty and disease severity at admission to better predict prognosis and guide clinical management in this population.