CLINICAL AND PARACLINICAL CHARACTERISTICS OF A GROUP OF PATIENTS WITH OVARIAN ENDOMETRIOMAS TREATED WITH LAPAROSCOPIC SURGERY AT HANOI OBSTETRICS AND GYNECOLOGY HOSPITAL FROM 2019 TO 2023

Khắc Hùng Trần 1,, Tuấn Đạt Đỗ 1,2, Đình Thoan Trần 3, Thị Hưởng Phạm 4, Thị Tuyết Lam Trịnh 4, Thị Hằng Nguyễn 4, Thị Anh Đào Lê1,2
1 Hanoi Medical University
2 Hanoi Obstetrics and Pediatrics Hospital
3 Thai Binh University of Medicine and Pharmacy
4 Hanoi Medical University Hospital

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Abstract

Objective: Describe the clinical and paraclinical characteristics of patients with endometriotic ovarian cysts who underwent laparoscopic surgery at Hanoi Obstetrics and Gynecology Hospital from 2019 to 2023. Subjects and Methods: A cross-sectional descriptive study was conducted on a sample of 260 patients diagnosed with ovarian endometrioma and treated with laparoscopic surgery at Hanoi Obstetrics and Gynecology Hospital from January 1, 2019, to December 31, 2023. Results: A study of 260 patients revealed a mean age of 35.86 ± 8.1 years (P<0.001), with 194 cases (74.5%) falling within the 30–49 age group. Chronic pelvic pain and dysmenorrhea were the most common clinical symptoms, observed in 73.1% and 36.5% of cases, respectively. Menstrual pain increased in patients with unilateral or bilateral ovarian endometriotic cysts (58.1%). On physical examination, most masses had a firm consistency (56.5%). Limited or absent mobility was found in the majority of cases (49.6%). Most tumors had well-defined borders with the uterus (66.2%), while 16.2% showed varying degrees of uterine invasion. Pain on examination was present in 87.7% of patients with varying intensity. Unilateral ovarian endometriomas (right or left ovary) were observed in 68.1% of cases, while bilateral involvement accounted for 31.9%. Moderate to severe pain (grades II and III) was reported by 71.5% of patients, and 21.2% experienced severe pain (grade IV) associated with complications (P<0.001). The mean size of the surgically removed cysts was 71 ± 24 mm. Elevated serum CA-125 levels were found in 77.7% of patients with ovarian cysts, while HE4 screening tests remained within normal limits in 93.8% of cases. Conclusion: The primary clinical symptoms include chronic pelvic pain and dysmenorrhea. The average size of surgically removed cysts is 65 ± 7.2 mm. There is an increasing tendency for the cysts to adhere to and invade surrounding pelvic organs, which poses significant challenges during laparoscopic surgery. Elevated serum CA-125 levels are found in the majority of cases, highlighting its value in disease screening and follow-up.

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References

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