FACTORS AFFECTING LEFT ATRIAL SIZE ONTHREE-DIMENSIONAL ECHOCARDIOGRAPHY IN PATIENTS WITH NON-VALVULAR ATRIAL FIBRILLATION

Đỗ Doãn Bách1,, Nguyễn Thị Thu Hoài1
1 Vietnam National Heart Institute, Bach Mai Hospital

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Abstract

Background: Left atrial (LA) enlargement is an important risk factor for incident stroke and a key determinant for the success of rhythm control strategies in patients with atrial fibrillation (AF). However, factors associated with LA volume in AF patients remain poorly understood. Objective: To study factors related to left atrial dilation in patients with non-valvular atrial fibrillation on 3D echocardiography. Methods: A cross-sectional descriptive study was conducted in patients with non-valvular atrial fibrillation. Data of medical history, clinical examination biochemical tests, ECG were collected. 2D and 3D echocardiography were performed in all participants and analyzed in a standardized manner. Left atrial volume was assessed on 3D echocardiography using Heart Model software. Results: From 07/2020 to 07/2021, 80 patients were included in the study, the mean age was 60.7 ± 4.8, male 48.8%, female 51.2%. Hypertension, diabetes mellitus, chronic kidney disease, coronary artery diseaseandleftventriculardiastolicdysfunction were associated with LA dilation on 3D echocardiography ( β=1.3 ± 0.9ml/m2 , β=0.8 ± 0.2 ml/m2,β=2.4 ± 0.9 ml/m2, β=2.2 ± 0.5ml/m2,β=2,3 ± 4.6 ml/m2). In multivariable analysis:Coronary artery disease, chronic kidney disease, left ventricular diastolic dysfunctionshowed an independent association with left atrial volume in patients with non-valvular atrial fibrillation (β=2,5 ± 0,4 ml/m2 ,β=2,9 ± 0,3 ml/m2 , β=2,4 ± 0,4 ml/m2, respectively). Conclusion: Left ventricular diastolic dysfunction, chronic kidney disease, and coronary artery disease are factors that affected left atrial volume in patients with nonvalvular atrial fibrillation.

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References

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