STUDY ON CLINICAL, HISTOPATHOLOGICAL CHARACTERISTICS AND THE ROLE OF IMAGING IN NON–MUSCLE-INVASIVE BLADDER CANCER AT CHO RAY HOSPITAL

Kinh Luân Thái 1,2,, Công Đức Lê 1
1 University of Medicine and Pharmacy at Ho Chi Minh City
2 Cho Ray Hospital

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Abstract

Objectives: To describe the clinical and histopathological characteristics and to evaluate the role of imaging modalities in the diagnosis of non–muscle-invasive bladder cancer (NMIBC) at Cho Ray Hospital. Materials and methods: A retrospective study was conducted on patients diagnosed with NMIBC from January 2019 to January 2024. Data on clinical presentation, imaging modalities (ultrasonography, computed tomography (CT), cystoscopy), and histopathology (T stage, histological grade, tumor characteristics) were analyzed. Results: A total of 156 cases were included, male (89.1%), with a mean age of 63.9 years. Gross hematuria was the main presenting symptom 78.8%. All patients underwent ultrasonography, CT, and cystoscopy. The tumor detection rate of ultrasonography was 36.5%, whereas both CT and cystoscopy achieved 100%. Stage Ta predominated 85.9%, and high-grade tumors accounted for 65.4%. Conclusion: In non–muscle-invasive bladder cancer, gross hematuria was the most common symptom 78.8%. Abdominal ultrasonography had a lower tumor detection rate at 36.5% compared with CT 100% and cystoscopy 100%. Most cases were diagnosed at stage Ta 85.9% with a predominance of high-grade histology 65.4%.

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References

1. Bray F, Laversanne M, Sung H, et al. Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. 2024;74(3):229-263.
2. Babjuk M, Burger M, Capoun O, et al. European Association of Urology Guidelines on Non-muscle-invasive Bladder Cancer (Ta, T1, and Carcinoma in Situ). European urology. 2022;81(1):75-94.
3. Joseph Z. Management Strategies for Non–Muscle-Invasive Bladder Cancer (Ta, T1, and CIS) Campbell-Walsh-Wein Urology. Elsevier; 2020:chap 136. page 3091-3111
4. Balci M, Tuncel A, Keten T, et al. Comparison of Monopolar and Bipolar Transurethral Resection of Non-Muscle Invasive Bladder Cancer. Urologia internationalis. 2018;100(1):100-104.
5. Wang L, Feng C, Ding G, et al. Ki67 and TP53 expressions predict recurrence of non-muscle-invasive bladder cancer. Tumour biology: the journal of the International Society for Oncodevelopmental Biology and Medicine. 2014;35(4):2989-95.
6. Hồ Xuân Tuấn, Nguyễn Văn Ân. Nhận xét thực trạng cắt đốt nội soi trong chẩn đoán bướu bàng quang không xâm lấn cơ. Y học TPHồ Chí Minh, chuyên đề Thận - Niệu. 2018;22(2):288-291.
7. Nguyễn Thanh Mộng, Nguyễn Phúc Cẩm Hoàng, Trần Trọng Huân. Ưu điểm phương pháp cắt đốt nội soi lấy nguyên khối bướu bàng quang bằng điện lưỡng cực. Tạp chí Y học TP Hồ Chí Minh. 2021;25(1):195-199.
8. Vollmer RT. A Review of Outcomes for Stage Ta Bladder Tumors. Am J Clin Pathol. 2016; 146(2):215-20.