NGHIÊN CỨU MỐI LIÊN QUAN VÔI HÓA ĐỘNG MẠCH CHỦ BỤNG VỚI THỜI GIAN MẮC BỆNH VÀ THỜI GIAN LỌC MÁU Ở BỆNH NHÂN BỆNH THẬN MẠN TÍNH GIAI ĐOẠN CUỐI

Abstract

Objectives: Analyzing the association between abdominal aortic calcification (AAC) by by non-contrast computed tomography (CT) scan with the detected-kidney disease duration, the dialysis duration in end-stage renal disease (ESRD) patients with/without dialysis. Methods: A prospective study was conducted involving 89 ESRD patients who were candidated for kidney transplantation at 103 Military Hospital. Non-contrast CT scan was performed to determine the aortic calcification index (ACI) as a semi-quantitative measure of AAC. Analyzing the univariate correlation and the multivariable logistic regression between AAC and detected-kidney disease duration, dialysis pre-transplant duration and some other factors. Results: There were 89 patients (68 males and 21 females), the median age was 36,0 years (Min-max: 18-66 years). AAC was observed in 67 patients (75,3%) (Median ACI: 4,82%), in which, there were 16 patients had severe calcification (ACI ≥ 20%).  Prevalence of AAC significantly increased with age, BMI, detected-kidney disease duration and dialysis pre-transplant duration (p < 0,05). AAC was significantly associated with age older than 30 (OR: 21,33; 25% CI: 5,116 - 88,96), detected-kidney disease duration (OR: 9,975; 95% CI: 3,326 - 29,914) and/or dialysis pre-transplant duration more than 1 year (OR: 7,179; 95% CI: 1,551 - 33,238). Conclusions: Detected-kidney disease duration and dialysis duration are significantly associated with the occurrence of AAC in ESRD patients.