CLINICAL OUTCOMES OF EARLY PHACOEMULSIFICATION IN ACUTE PRIMARY ANGLE CLOSURE

Kim Thành Đoàn 1,2, Đăng Tâm Mai 2, Thất Hoàng Quân Tôn 1,
1 Pham Ngoc Thach University of Medicine, Ho Chi Minh City
2 Eye Hospital of Ho Chi Minh City

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Abstract

Introduction: Acute primary angle closure (APAC) is an ophthalmic emergency, most commonly resulting from pupillary block. Laser peripheral iridotomy (LPI) is the first-line treatment; however, it often fails to achieve sustained intraocular pressure (IOP) control and significant improvement in anterior chamber angle parameters. Phacoemulsification effectively eliminates the pupillary block and removes the lens component involved in the pathogenesis of angle closure diseases. Objective: To evaluate the changes in visual acuity (VA) and IOP following early phacoemulsification with intraocular lens implantation in APAC patients treated at the Glaucoma Department, Ho Chi Minh City Eye Hospital. Methods: A 6-month prospective longitudinal study was conducted on 34 patients with unilateral APAC. All patients underwent early phacoemulsification with posterior chamber intraocular lens implantation. Postoperative follow-ups were performed at 1, 3, and 6 months. Results: The study included 28 females and 6 males, with a mean age of 58,38 ± 7,01 years. Preoperatively, the LogMAR VA and IOP of the affected eyes were significantly worse than those of the fellow eyes (LogMAR VA: 1,24 ± 0,74 and 0,18 ± 0,13, p<0,001; IOP: 50,19 ± 8,78mmHg and 14,69 ± 2,41mmHg, p<0,001). More than 75% of the affected eyes had VA in the moderate-to-severe impairment group, according to the WHO 2015 classification. One month postoperatively, the mean LogMAR VA was 0,26 ± 0,36, which was statistically significantly lower compared to the preoperative VA (p<0,001). Thirty-two out of 34 affected eyes achieved good visual acuity, which remained stable throughout the 6-month follow-up period. The mean IOP in the affected eyes decreased by 12,82 ± 2,74mmHg mmHg at 1 month post-surgery and was statistically significantly lower than the preoperative IOP (p<0.001). The IOP remained stable within the normal range at all follow-up time points. No cases of recurrent IOP elevation were recorded during the follow-up. Conclusion: Early phacoemulsification is an effective treatment for acute primary angle closure, providing significant and sustained improvement in visual acuity and long-term intraocular pressure control.

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References

1. Moussa, G., K. Bassilious, and N.J.A.O. Mathews. A novel excel sheet conversion tool from Snellen fraction to LogMAR including'counting fingers','hand movement','light perception'and'no light perception'and focused review of literature of low visual acuity reference values. 2021; 99(6).
2. Anbar, M.A., et al. Angle, anterior chamber parameters, and intraocular pressure changes after early phacoemulsification in acute angle-closure glaucoma. 2023; 49(11):1147-1152.
3. Lam, D.S., et al. Randomized trial of early phacoemulsification versus peripheral iridotomy to prevent intraocular pressure rise after acute primary angle closure. 2008; 115(7):1134-1140.
4. Moghimi, S., et al. Acute angle closure: qualitative and quantitative evaluation of the anterior segment using anterior segment optical coherence tomography. 2014; 42(7):615-622.
5. He, M., et al. Anterior chamber depth in elderly Chinese: the Liwan eye study. 2008; 115(8):1286-1290. e2.
6. Moghimi, S., et al. Early phacoemulsification in patients with acute primary angle closure. 2015; 27(3-4):70-75.
7. Lin, Y.-H., et al. Early versus Delayed Phacoemulsification and Intraocular Lens Implantation for Acute Primary Angle‐Closure. 2020; 2020(1):8319570.
8. Zhao, R., et al. Assessing the clinical efficacy of phacoemulsification cataract extraction in treating acute primary angle closure and fellow primary angle closure suspect eyes using AS-OCT. 2024; 11:1436991.
9. Aung, T., et al. Acute primary angle-closure: long-term intraocular pressure outcome in Asian eyes. 2001; 131(1):7-12.
10. Li, S.-W., et al. Angle parameter changes of phacoemulsification and combined phacotrabeculectomy for acute primary angle closure. 2015; 8(4):742