ĐẶC ĐIỂM LÂM SÀNG, CẬN LÂM SÀNG VÀ KẾT QUẢ ĐIỀU TRỊ SỐT MÒ Ở TRẺ EM

Abstract

To describe the clinical and paraclinical characteristics of pediatric patients with scrub typhus, we conducted a combined retrospective and prospective descriptive study on children treated at the Vietnam National Children’s Hospital from January 2020 to July 2025. The results showed a male predominance (61.54%) and a high proportion of patients living in rural areas (88.46%). Fever was present in all cases (100%). Other common clinical signs included eschar (65.38%), lymphadenopathy (38.84%), rash (23.08%), peripheral edema (34.62%), ascites (64.15%), hepatomegaly (64.38%), and splenomegaly (48.08%). Laboratory findings revealed moderate anemia in 63.46% of patients and leukocytosis in 57.69%. Neutrophil counts were below 60% in 82.7% of cases, and thrombocytopenia was observed in 67.31%. Elevated liver enzymes were frequently noted: AST (GOT) > 40 U/L in 93.2% and increased ALT (GPT) in 88.6% of patients. Hypoalbuminemia was found in 88.10% of cases. The overall mortality rate was 1.92%. Intravenous chloramphenicol and oral doxycycline were both found to be similarly effective in the treatment of pediatric scrub typhus.