THE TREATMENT RESULT OF THREATENED PRETERM LABOR BY NIFEDIPINE AT THAI NGUYEN NATIONRAL HOSPITAL
Main Article Content
Abstract
Objective: To evaluate the treatment result threatened preterm labor by Nifedipine at Thai Nguyen national hospital from from June 1, 2024 to May 31, 2025. Study subject and methods: A cross-sectional descriptive study was conducted on 72 pregnant women with threatened premature labor which have gestational age from 22 to 36 weeks at Thai Nguyen national hospital. Results: The proportion of pregnant women had hospital admitted at 32-36 weeks of gestational age was 59.8%; 32-34 weeks of gestational age was 29.2% and 28-31 weeks was 23.6%. The success proportion of treatment by Nifedipine was 90.3%. The success proportion was higher in the group with contraction frequency ≤3 times and cervical dilation ≤1 cm compared to the other group (p<0.05). The proportion of prolonged pregnancy >28 days was 65.3%; prolonged pregnancy 15-28 days was 19.4% and from 8-14 days was 5.6%. The proportion of adverse drug reaction was headache 6.9% and nausea 6.9%. Conclusion: Nifedipine is a drug for treating threatened premature labor with very high results and ensuring safety.
Article Details
Keywords
Threatened preterm labor, Nifedipine, treatment result.
References
2. Nguyễn Thị Hồng, Nguyễn Phương Sinh, Đỗ Tuấn Đạt, và cs. (2024), "Đặc điểm và kết quả điều trị dọa đẻ non bằng Nifedipine tại Bệnh viện Sản Nhi Bắc Ninh", Tạp chí Phụ sản,, 22 (3), tr. 25-30.
3. Nguyễn Thị Hồng, Nguyễn Phương Sinh (2024), "Một số yếu tố ảnh hưởng đến kết quả điều trị dọa đẻ non bằng Nifedipine tại Bệnh viện Sản Nhi Bắc Ninh", Tạp chí Y học cộng đồng, 56 (Số đặc biệt 12), tr. 104-109.
4. Phạm Chí Kông, Huỳnh Kim Quang (2025), "Hiệu quả của Nifedipine trong điều trị dọa sinh non", Tạp chí Y Dược Huế,, 15 (5), tr. 163-169.
5. Bùi Đặng Minh Trí, Bùi Đặng Lan Hương, Nguyễn Việt Thành (2023), "Hiệu quả cắt cơn gò tử cung và tác dụng không mong muốn của Nifedipine trong điều trị dọa sinh non", Tạp chí Y học cộng đồng, 64 (5), tr. 19-26.
6. De Heus R., Mulder E.J., and Visser G.H. (2010), "Management of preterm labor: atosiban or nifedipine?", Int J Womens Health, 2, pp. 137-42.
7. Wilson A., Hodgetts-Morton V.A., Marson E.J., et al. (2022), "Tocolytics for delaying preterm birth: a network meta-analysis (0924)", Cochrane Database Syst Rev, 8 (8), pp. Cd014978.
8. Tijn M.S. van Winden, Tobias A. J. Nijman, C. Emily Kleinrouweler, et al. (2022), "Tocolysis with nifedipine versus atosiban and perinatal outcome: an individual participant data meta-analysis", BMC Pregnancy and Childbirth, 22 (1), pp. 567.