ĐẶC ĐIỂM THAI PHỤ NHIỄM HBV VÀ ĐIỀU TRỊ DỰ PHÒNG LÂY TRUYỀN VIÊM GAN VI RUS B TỪ MẸ SANG CON TẠI BỆNH VIỆN SẢN NHI PHÚ THỌ NĂM 2023

Abstract

Objective: Describe the characteristics of pregnant women infected with HBV and the current status of HBV prevention transmission from mother to child at Phu Tho Obstetrics and Pediatrics Hospital. Subjects and Methods: Retrospective cross-sectional description on 194 medical records of pregnant women infected with HBV who came for examination and gave birth in 2023. Results: 80.4% of pregnant women were newly diagnosed with HBV infection during this pregnancy, mainly in the last trimester, accounting for 60.8%. Only 33% (64/194) of pregnant women were tested for HBV DNA viral load. Of them, 24/64 (37.5%) had HBV DNA below the threshold of detection, and 34/64 (53.1%) were indicated for antiviral treatment for hepatitis B. 12/34 (35.2%) received TDF treatment late, after 28 weeks. Of the newborns, 90.2% received the hepatitis B vaccine and 82.0% received HBIG within the first 24 hours. 149 out of 194 infants (76.8%) received both the vaccine and HBIG according to standard procedures, and 23.2% of mother-child pairs received standard preventive measures as recommended. Conclusion: The rate of adherence to standard preventive measures for mother-to-child transmission of HBV is still low. Better coordination between obstetrics, infectious disease, and pediatrics specialists is needed to improve the rate of early prevention transmission from mother to child.