NGHIÊN CỨU NỒNG ĐỘ NT-PROBNP TRÊN BỆNH NHÂN SUY TIM TẠI BỆNH VIỆN ĐA KHOA VÂN ĐÌNH NĂM 2025

Abstract

Objective: This study aimed to describe NT-proBNP concentrations in patients with heart failure and to investigate the relationship between NT-proBNP concentrations and the severity of heart failure according to NYHA classification. Subjects and methods: Cross-sectional, retrospective and prospective descriptive study on 105 patients with heart failure according to NYHA classification from January 2025 to September 2025 at the Department of Cardiology - Geriatrics, Van Dinh General Hospital. Results: The mean age of the study group was 79.84 ± 10.99 years; 65.7% were female. The mean BMI was 20.89 ± 2.42 kg/m². The most common symptoms were dyspnea (87.6%) and fatigue (85.7%). The mean NT-proBNP concentration increased gradually according to NYHA level, lowest in NYHA I (1,733.15 ± 1,179.31 pg/mL), highest in NYHA IV (14,076.69 ± 13,067.52 pg/mL) (p < 0.001) and had a positive correlation. NT-proBNP tended to be higher in women and increased gradually with age but was not statistically significant (p > 0.05). The BMI ≥ 23 kg/m² group had higher NT-proBNP than the BMI < 23 kg/m² group (p = 0.036). Conclusion: NT-proBNP levels increased gradually with NYHA heart failure severity, reflecting a positive correlation between NT-proBNP and heart failure severity. Female patients, older patients, and patients with BMI ≥ 23 kg/m² tended to have higher NT-proBNP levels, requiring regular monitoring to assess heart failure progression.