ĐÁNH GIÁ TÌNH TRẠNG DỰ TRỮ SẮT Ở BỆNH NHÂN THẬN NHÂN TẠO CHU KỲ TẠI BỆNH VIỆN THANH NHÀN

Abstract

Objectives: To assess iron stores in patients undergoing maintenance hemodialysis at Thanh Nhan Hospital and to examine the association between iron status and selected clinical and laboratory variables. Subjects and Methods: A cross-sectional descriptive study was conducted on 110 patients receiving maintenance hemodialysis at the Department of Artificial Kidney, Thanh Nhan Hospital, from March 2024 to September 2024. Results: The mean age of the study population was 51.8 ± 11.6 years, with the majority distributed in the age groups 31–50 years (39.1%) and 51–70 years (34.54%). The mean hemoglobin concentration was 93.8 ± 11.3 g/L. Anemia was present in 87.3% of patients, predominantly mild anemia. The mean serum iron concentration was 14.8 ± 7.5 µmol/L; mean ferritin level 546 ± 152 ng/mL; mean transferrin concentration 161 ± 32.7 mg/dL; and mean transferrin saturation (TSAT) 37.5 ± 19.2%.Ferritin levels showed a positive correlation with RET-He (r = 0.11), serum creatinine (r = 0.269), body mass index (r = 0.111), dialysis vintage (r = 0.126), and hemoglobin concentration (r = 0.12), all with p < 0.05. Serum iron demonstrated a positive correlation with creatinine (r = 0.172), total protein (r = 0.148), albumin (r = 0.255), and RET-He (r = 0.28) (p < 0.05). Transferrin concentration was positively associated with serum albumin (r = 0.065, p < 0.05). TSAT exhibited a positive correlation with serum albumin (r = 0.287) and RET-He (r = 0.165), both with p < 0.05