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Date Published: 09/02/2026
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DOI: https://doi.org/10.51298/vmj.v559i1.17440
Issue
Vol. 559 No. 1 (2026)
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Các bài báo
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Phạm, T. T. G., & Trương, V. L. (2026). EVALUATION OF THE EFFECTIVENESS OF CONTINUOUS RENAL REPLACEMENT THERAPY USING THE OXIRIS HEMOFILTER IN THE MANAGEMENT OF SEVERE ACUTE PANCREATITIS AT THANH NHAN HOSPITAL. Vietnam Medical Journal, 559(1). https://doi.org/10.51298/vmj.v559i1.17440

EVALUATION OF THE EFFECTIVENESS OF CONTINUOUS RENAL REPLACEMENT THERAPY USING THE OXIRIS HEMOFILTER IN THE MANAGEMENT OF SEVERE ACUTE PANCREATITIS AT THANH NHAN HOSPITAL

Thi Trà Giang Phạm, Vinh Long Trương

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Abstract

Objective: To describe the clinical and laboratory characteristics of patients with severe acute pancreatitis (SAP), and to evaluate the effectiveness of continuous renal replacement therapy (CRRT) using the Oxiris hemofilter in the management of SAP. Methods: A prospective interventional study was conducted on 27 patients diagnosed with severe acute pancreatitis who received treatment at Thanh Nhan Hospital from January 2024 to September 2025. Results: Among the 27 patients included in the study, no mortality was recorded. Following CRRT with the Oxiris filter, serum IL-6 levels markedly decreased from 623 to 64 pg/mL; leukocyte counts decreased from 14.8 to 9.2 G/L. Respiratory rate improved significantly from 31.3 ± 4.5 to 18.2 ± 3.6 breaths per minute. The APACHE II score was also reduced from 14.3 ± 3.9 to 9.8 ± 1.8 after treatment.

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References

1. Yadav D. and Lowenfels A.B (2013). The Epidemiology of Pancreatitis and Pancreatic Cancer. Gastroenterology, 144(6), 1252–1261.
2. Saullo P, Caronna R, Angelici AM, Rinaldi V, Liberatori G, Mingoli A, Chirletti P. Value of continuous hemofiltration in patients with severe acute pancreatitis at onset: single-centre experience on 48 patients. J Clin Med. 2025 Sep 21;14(18):6647.
3. Nguyễn Anh Tuấn. Đặc điểm lâm sàng và kết quả điều trị viêm tụy cấp nặng theo phân độ CTSI tại Bệnh viện Bạch Mai. Tạp chí Y học Việt Nam. 2022; 521(2):45–52.
4. Forsmark CE, Vege SS, Wilcox CM. Acute Pancreatitis. N Engl J Med. 2016;375(20):1972–1981.
5. Nguyễn Tài Thu. Nghiên cứu giá trị tiên lượng tử vong của chỉ số áp lực ổ bụng (IAP) ở bệnh nhân hồi sức. Tạp chí y dược lâm sang 108. 2020;15(8):44–48.
6. Mounzer R, Langmead CJ, Wu BU, et al. Comparison of BISAP, Ranson’s, APACHE-II, and CTSI in predicting organ failure and mortality in acute pancreatitis. Am J Gastroenterol. 2012;107(3):435–444.
7. Đinh Văn Trung, Phạm Thị Thanh Mai. Đánh giá hiệu quả của biện pháp lọc máu liên tục trong phối hợp điều trị viêm tụy cấp nặng tại bệnh viện đa khoa tỉnh Phú Thọ. Tạp chí Y học Việt Nam. 2023;523(2):56–59.