NGHIÊN CỨU ĐẶC ĐIỂM LÂM SÀNG, CẬN LÂM SÀNG VÀ MỘT SỐ YẾU TỐ LIÊN QUAN ĐẾN CHUYỂN DẠNG CHẢY MÁU Ở BỆNH NHÂN NHỒI MÁU NÃO DO TẮC ĐỘNG MẠCH NÃO GIỮA TẠI BỆNH VIỆN THANH NHÀN

Abstract

Objective: To characterize the clinical and paraclinical features and to assess factors associated with hemorrhagic transformation in patients with middle cerebral artery infarction complicated by hemorrhagic conversion at Thanh Nhan Hospital. Subjects and methods: A cross-sectional case series was conducted on 28 patients with middle cerebral artery infarction treated at Thanh Nhan Hospital from March 2025 to September 2025. Results: Mean age of patients with hemorrhagic transformation was 69.07 ± 10.84 years, males accounting is 42.9%. The most frequent clinical presentation was hemiparesis (78.6%). The mean NIHSS score at admission and at the time of hemorrhagic transformation was 10.64 ± 8.25 and 11.93 ± 8.27. The mean systolic blood pressure was 153.57 ± 26.49 mmHg. On neuroimaging, large-territory infarctions with lesion size > 30 mm accounted for 64.3%, and parenchymal hematoma was observed in 64.3% of cases. Factors contributing to the prediction of hemorrhagic transformation included systolic blood pressure (OR = 6.250, 95% CI: 1.213–32.214) and infarct size > 30 mm (OR = 6.600, 95% CI: 1.229–35.438).