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Date Published: 07/03/2026
Abstract Views: 48
Views PDF: 17
DOI: https://doi.org/10.51298/vmj.v559i2.17463
Issue
Vol. 559 No. 2 (2026)
Section
Các bài báo
How to Cite
Phạm , Q. H., Bùi , T. N. H., Nguyễn , T. C., & Phạm , H. Y. (2026). MEASUREMENT UNCERTAINTY OF HbA1C TESTING AT THE HANOI FRENCH HOSPITAL IN 2025. Vietnam Medical Journal, 559(2). https://doi.org/10.51298/vmj.v559i2.17463

MEASUREMENT UNCERTAINTY OF HbA1C TESTING AT THE HANOI FRENCH HOSPITAL IN 2025

Quỳnh Hoa Phạm 1, Thị Ngọc Hà Bùi 2,, Trường Chung Nguyễn 1, Hải Yến Phạm 1
1 Hanoi French Hospital
2 Hanoi University of Public Health

Main Article Content

Abstract

Objective: To determine the measurement uncertainty using the top-down approach for theHbA1c test at Hanoi French Hospital in 2025. Methods: This was an applied experimental study conducted at Hanoi French Hospital. Internal quality control data from April to July 2025 and external quality control data from February to July 2025 were collected to calculate the expanded measurement uncertainty (U) according to CLSI EP29-A guidelines. Results: The expanded measurement uncertainty of the HbA1c test was 4.57%. This value was within the acceptable limit of the maximum measurement uncertainty set by RiliBÄK (6.1%) but did not meet the standards of EFLM (1.8%) and CLIA (3.7%). The expanded uncertainty of the HbA1c test (4.57%) was slightly higher than the total error (TE) of 4.49% and exceeded the allowable total error (TEa) defined by Ricos and EFLM but was lower than the TEa limit defined by CLIA (8.0%). Conclusion: The HbA1c test meets the RiliBÄK (Germany) standard for clinical use. However, further quality improvement is needed to meet the stricter criteria of EFLM and CLIA.

Article Details

Keywords

measurement uncertainty, top-down approach, CLSI EP29-A, HbA1c test, ISO 15189.

References

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