ĐÁNH GIÁ KẾT QUẢ HÓA XẠ TRỊ TIỀN PHẪU UNG THƯ TRỰC TRÀNG BẰNG KĨ THUẬT VMAT KẾT HỢP CAPECITABINE ĐƯỜNG UỐNG TẠI BỆNH VIỆN K

Abstract

Objective: Clinical and subclinical characteristics of rectal cancer patients at K Hospital from 06/2018 to 10/2021. Evaluation of the results of preoperative radio-chemotherapy for rectal cancer by Volumetric  Modulation Arc Therapy (VMAT) combined with oral capecitabine. Subjects and research methods: Non-controlled clinical intervention study, convenient sample size. Results: Mean age was 58.6 years old. The common age is from 51 to 70, accounting for 76.6%. Ratio male/female: 1.4. Disease detection time ≤ 6 months accounted for 84.9%. Common symptoms in colorectal cancer include bloody stools 87.2%. Partially mobile tumors accounted for 65.5%. Adenocarcinoma accounts for 100%, mucinous form accounts for 14.8%. Stage T3 accounted for 61.8%, T4 accounted for 29.1%. After treatment, the tumor circumference decreased by 70.9%. Rate of lowering stage 64.1%. The rate of radical surgery is 100%, in which low rectal cancer preserves the sphincter 16.4%. Response on MBH accounts for 90.9%. Conclusion: The average age is 58.6. Ratio male/female: 1.4. Time of disease detection ≤ 6 months accounted for 84.9%. Common functional symptoms: bloody stools, accounting for 87.2%. Partial mobility accounts for 74.5%. Stage T3 accounted for 64.8%, T4 accounted for 35.2%. Tumors less than 6 cm from the anal margin account for 72.6%. Lower the overall period 64.1%. Increase the rate of radical surgery by 100% and anal sphincter-conserving surgery to 16.4%. The general histopathological response was 90.9%. In which complete response is 10.9%. Toxicity only encountered grade 1, grade 2 with a low rate.