CLINICAL AND PARACLINICAL CHARACTERISTICS OF NEW VERTEBRAL COMPRESSION FRACTURES AFTER VERTEBRAL CEMENT AUGMENTATION IN OSTEOPOROSIS PATIENTS

Văn Trung Nguyễn, Đăng Tân Lê, Đức Hoàng Nguyễn

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Abstract

Background: New-onset vertebral compression fractures (VCFs) after vertebral cement augmentation (VCA) represent a significant complication in osteoporotic patients. Understanding the clinical and paraclinical characteristics of these cases is essential for improving management. Objective: To identify the clinical and paraclinical features of patients who developed new VCFs after VCA. Methods: A retrospective study of 58 patients with new VCFs following VCA at Bach Mai Hospital, with a mean follow-up of 24.79 months. Results: Patients had a mean age of 72.9 years, were predominantly female, and had low BMI and severe osteoporosis (mean T-score –4.2). Most fractures were spontaneous or due to minor trauma. Initial augmentation was commonly at the thoracolumbar junction; 39.7% underwent multi-level augmentation. Adjacent fractures occurred in 60.3% of cases. Higher ASA scores, long-term corticosteroid use, diabetes, and multi-level procedures showed a trend toward increased adjacent fractures. Conclusions: New VCFs after VCA mainly occur in elderly, severely osteoporotic patients. Factors such as higher ASA class and chronic corticosteroid therapy may contribute to adjacent-level fractures.

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References

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