SOME FACTORS RELATED TO GOUT AT NINH BINH PROVINCIAL GENERAL HOSPITAL IN 2025

Phương Dung Hoàng 1,, Thị Thuỷ Nguyễn 1, Văn Dung Đỗ 2
1 Ninh Binh General Hospital
2 Thai Binh University of Medicine and Pharmacy

Main Article Content

Abstract

Gout is a microcrystalline arthritis, characterized by recurrent acute arthritis attacks, with deposition of sodium urate crystals in tissues, caused by increased uric acid in the blood. Objective: Describe some factors associated with gout in the study group in 2025. Subjects and methods: Cross-sectional descriptive study, with analysis on 145 gout patients who came to Ninh Binh General Hospital for examination and treatment in 2025. Results: Multivariate linear regression model identified 5 clinical and paraclinical signs that were associated with the number of flare-ups (with p<0.05), including: history of using colchicine, allopurinol, traditional medicine; pain level, blood uric acid, and joint damage on X-ray; Patients in the chronic gout stage were associated with clinical and paraclinical signs (with p<0.05), including: history of using colchicine, corticosteroids, allopurinol, fehuxostat; adrenal insufficiency, lack of physical exercise, and joint damage. Conclusion: The number of gout flare-ups increased and the chronic gout stage was associated with a history of using certain gout medications, adrenal insufficiency, lack of physical exercise, high blood uric acid, and gouty joint damage.

Article Details

References

1. Prevalence of gout and hyperuricemia in the US general population: The National Health and Nutrition Examination Survey 2007–2008. doi:10.1002/art.30520
2. Zhang Q, Gong H, Lin C, et al. The prevalence of gout and hyperuricemia in middle-aged and elderly people in Tibet Autonomous Region, China: A preliminary study. Medicine (Baltimore). 2020;99(2): e18542. doi:10.1097/MD. 0000000000018542
3. Liu HH, Li JJ. Aging and dyslipidemia: A review of potential mechanisms. Ageing Research Reviews. 2015;19:43-52. doi:10.1016/j.arr.2014. 12.001
4. Cox P, Gupta S, Zhao SS, Hughes DM. The incidence and prevalence of cardiovascular diseases in gout: a systematic review and meta-analysis. Rheumatol Int. 2021;41(7):1209-1219. doi:10.1007/s00296-021-04876-6
5. FitzGerald JD, Dalbeth N, Mikuls T, et al. 2020 American College of Rheumatology Guideline for the Management of Gout. Arthritis Care Res (Hoboken). 2020;72(6):744-760. doi:10.1002/acr.24180
6. Wortmann RL. Gout and hyperuricemia. Curr Opin Rheumatol. 2002;14(3):281-286. doi:10. 1097/00002281-200205000-00015
7. Nguyễn TTH. Đánh giá tỷ lệ suy thượng thận ở bệnh nhân gút mạn có tiền sử dùng corticoid kéo dài tại Bệnh viện Nội tiết Trung ương. In: Luận Văn Thạc Sĩ y Học. Trường Đại học Y Hà Nội; 2020.
8. Trần MH. Đặc Điểm Hoạt Động Thể Lực và Chế Độ Sinh Hoạt ở Bệnh Nhân Gút Điều Trị Tại Bệnh Viện Bạch Mai Năm 2021. Luận văn Thạc sĩ Y học; 2021.