SOME FACTORS RELATED TO GOUT AT NINH BINH PROVINCIAL GENERAL HOSPITAL IN 2025
Main Article Content
Abstract
Gout is a microcrystalline arthritis, characterized by recurrent acute arthritis attacks, with deposition of sodium urate crystals in tissues, caused by increased uric acid in the blood. Objective: Describe some factors associated with gout in the study group in 2025. Subjects and methods: Cross-sectional descriptive study, with analysis on 145 gout patients who came to Ninh Binh General Hospital for examination and treatment in 2025. Results: Multivariate linear regression model identified 5 clinical and paraclinical signs that were associated with the number of flare-ups (with p<0.05), including: history of using colchicine, allopurinol, traditional medicine; pain level, blood uric acid, and joint damage on X-ray; Patients in the chronic gout stage were associated with clinical and paraclinical signs (with p<0.05), including: history of using colchicine, corticosteroids, allopurinol, fehuxostat; adrenal insufficiency, lack of physical exercise, and joint damage. Conclusion: The number of gout flare-ups increased and the chronic gout stage was associated with a history of using certain gout medications, adrenal insufficiency, lack of physical exercise, high blood uric acid, and gouty joint damage.
Article Details
Keywords
gout, gout flare-ups, acute gout, chronic gout.
References
2. Zhang Q, Gong H, Lin C, et al. The prevalence of gout and hyperuricemia in middle-aged and elderly people in Tibet Autonomous Region, China: A preliminary study. Medicine (Baltimore). 2020;99(2): e18542. doi:10.1097/MD. 0000000000018542
3. Liu HH, Li JJ. Aging and dyslipidemia: A review of potential mechanisms. Ageing Research Reviews. 2015;19:43-52. doi:10.1016/j.arr.2014. 12.001
4. Cox P, Gupta S, Zhao SS, Hughes DM. The incidence and prevalence of cardiovascular diseases in gout: a systematic review and meta-analysis. Rheumatol Int. 2021;41(7):1209-1219. doi:10.1007/s00296-021-04876-6
5. FitzGerald JD, Dalbeth N, Mikuls T, et al. 2020 American College of Rheumatology Guideline for the Management of Gout. Arthritis Care Res (Hoboken). 2020;72(6):744-760. doi:10.1002/acr.24180
6. Wortmann RL. Gout and hyperuricemia. Curr Opin Rheumatol. 2002;14(3):281-286. doi:10. 1097/00002281-200205000-00015
7. Nguyễn TTH. Đánh giá tỷ lệ suy thượng thận ở bệnh nhân gút mạn có tiền sử dùng corticoid kéo dài tại Bệnh viện Nội tiết Trung ương. In: Luận Văn Thạc Sĩ y Học. Trường Đại học Y Hà Nội; 2020.
8. Trần MH. Đặc Điểm Hoạt Động Thể Lực và Chế Độ Sinh Hoạt ở Bệnh Nhân Gút Điều Trị Tại Bệnh Viện Bạch Mai Năm 2021. Luận văn Thạc sĩ Y học; 2021.