CLINICAL AND PARACLINICAL CHARACTERISTICS OF ACUTE XACERBATIONS IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE WITH DIABETES MELLITUS
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Abstract
Objective: To describe the clinical characteristics of patients with acute exacerbations of chronic obstructive pulmonary disease (COPD) with diabetes mellitus and to examine the relationship between blood glucose and the severity of COPD exacerbations. Subjects and methods: This descriptive study included 53 patients with acute exacerbations of COPD with diabetes mellitus at the General Internal Medicine Department of Thanh Nhan Hospital from March to November 2025. Results: The average age of the patients studied was 72.43 ± 5.83, with 79.2% being male; the most common comorbidity was hypertension (HTN); 47.1% of patients were in group E; 86.8% of patients had mMRC ≥ 2 points; and 79.2% had CAT ≥ 10 points. 69.8% of patients experienced severe exacerbations according to the Anthonisen classification. Common symptoms included increased shortness of breath (85.9%), increased cough, increased sputum production (90.6%), and changes in sputum color (81.1%). 52.6% of patients had HbA1c ≥7%, and 52.8% had blood glucose levels >7.8 mmol/l upon admission. The proportion of patients with elevated blood glucose levels upon admission experiencing severe exacerbations was higher than the group without elevated blood glucose, with a statistically significant difference (p<0.05).
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References
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