ĐẶC ĐIỂM LÂM SÀNG VÀ CẬN LÂM SÀNG CỦA U LYMPHO KHÔNG HODGKIN BIỂU HIỆN TẠI XƯƠNG TẠI BỆNH VIỆN K

Abstract

Objective: Describe the clinical and paraclinical characteristics of Bone lymphoma. Subjects and methods: A cross-sectional descriptive prospective study was conducted on 76 patients with bone lymphoma treated with chemotherapy at the Hematologic Oncology Department, K Hospital from May 2019 to October 2025. Results: The median age was 53; The male/female ratio was ~1.05; PS=0 accounted for 65.8%. B symptoms occurred in 18.4% of patients; Pathological fracture rate 6.6%; osteolytic lesion rate 72.4%; DLBCL disease type accounts for the majority 5.7%; The most common bone lesion location is the vertebrae 42.1%; pelvic bone lesion rate 34.2%; skull bone lesion account for 25%; femur lesion account for 19.7%; most patients are in the late stage - secondary lymphoma in bone 75%, 25% of patients are diagnosed with primary lymphoma in bone. Conclusion: The characteristic clinical features of bone lymphoma support doctors in the process of early diagnosis and timely and appropriate treatment selection for these patients.