ATYPICAL TRIGEMINAL NEURALGIA: EFFECTIVENESS OF ULTRASOUND-GUIDED PTERYGOPALATINE GANGLION BLOCK

Viết Thắng Lê, Hoàng Tuấn Dũng Bùi

Main Article Content

Abstract

Objective: Atypical Trigeminal Neuralgia (ATN) is a type of chronic facial pain characterized by a dull, burning, and continuous pain, different from the typical paroxysmal pain. The disease has a major impact on the patient's quality of life and ability to function. Ultrasound-guided pterygopalatine ganglion block (PPGB) is a minimally invasive intervention technique, expected to bring effective pain relief to drug-resistant patients. To evaluate the effectiveness and safety of ultrasound-guided pterygopalatine ganglion block in the treatment of atypical trigeminal neuralgia. Subjects and methods: A prospective, single-center observational study conducted at the University of Medicine and Pharmacy Hospital, Ho Chi Minh City, from August 2024 to August 2025, including 32 ATN patients, of which 30 patients completed 12 weeks of follow-up. Patients underwent acromioclavicular ganglion block using a mixture of bupivacaine 0.5% (2–3 mL) and dexamethasone 2 mg, under ultrasound guidance via the subzygomatic approach. Pain severity was assessed by the NRS scale, quality of life by the SF-36, and patient satisfaction. Results: The mean NRS score decreased from 7.8 ± 1.1 to 2.7 ± 1.3 after 12 weeks (p < 0.001). The proportion of patients achieving ≥50% pain relief was 73.3% at week 1, 83.3% at week 4, and 86.7% at week 12. There were no serious complications; 16.7% of patients experienced transient maxillary numbness. 83.3% of patients were “very satisfied” with the procedure. Conclusion: Ultrasound-guided acromioclavicular ganglion block is a safe and effective method in the treatment of atypical trigeminal neuralgia, significantly reducing pain, improving quality of life and reducing the need for pain medication.

Article Details

References

1. Araya EI, Claudino RF, Piovesan EJ, Kowacs PA, Werneck LC. Trigeminal neuralgia: basic and clinical aspects. Curr Neuropharmacol. 2010;8(4):297-310. doi:10.2174/157015910792246253.
2. Bendtsen L, Zakrzewska JM, Abbott J, et al. European Academy of Neurology guideline on trigeminal neuralgia management. Eur J Neurol. 2019;26(6):831–849.
3. Cohen S, Zada Y, Sudhakar A, et al. Ultrasound-guided pterygopalatine ganglion block for facial pain: review of techniques and outcomes. Reg Anesth Pain Med. 2019;44(5): 655–661.
4. Huang JH, Chang CN, Ling CM. Ultrasound-guided nerve block techniques for trigeminal neuralgia: a case series. Pain Physician. 2016;19(8):E1081–E1087.
5. Menzies JA, Hawkins D, Rickards EP. The role of dexamethasone in regional anesthesia: impact on outcomes and side effects. J Pain Res. 2019;12:217-223.
6. Nader A, Kendall MC, De Oliveira GS, et al. Ultrasound-guided trigeminal nerve block via the pterygopalatine fossa: an effective treatment for trigeminal neuralgia. Pain Physician. 2013;16(5): E537–E545.
7. Piagkou M, Demesticha T, Troupis T, et al. The pterygopalatine ganglion and its role in various pain syndromes: a review. Pain Pract. 2012;12(5):399–409.
8. Slonim S, Melnyk N. Advances in treatment of facial pain: from blocks to neuromodulation. Pain Ther. 2021;10(4):1209–1227.
9. Totzeck A, Pham M, Lee DH, et al. Efficacy and safety of pterygopalatine ganglion blocks in facial pain syndromes: a systematic review. Clin J Pain. 2017;33(9):834–844.