PREVALENCE OF DEEP VEIN THROMBOSIS IN PATIENTS WITH MAJOR LOWER LIMB FRACTURES

Đăng Phú Hà Nguyễn, Lê Minh Thống Nguyễn, Mã Phương Duy Huỳnh

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Abstract

Background: Deep vein thrombosis  is a silent yet dangerous condition caused by various factors, including trauma, lower limb fractures, and internal medical conditions. Surgical interventions for major lower limb fractures increase the risk of developing deep vein thrombosis. Objectives: To determine the prevalence of deep vein thrombosis and investigate some risk factors associated with deep vein thrombosis in patients with major lower limb fractures. Methods: This prospective descriptive study was conducted on patients with major lower limb fractures diagnosed and treated at the Orthopedic Department of Gia Dinh People's Hospital. All patients were assessed using the Caprini risk score and underwent Doppler ultrasound of the lower limb veins at admission and post-surgery. Results: Among 90 patients with major lower limb fractures, the deep vein thrombosis incidence was 18.8% (17/90 patients). Hypertension (15/17 cases), length of hospital stay (p= 0.009), and femur fractures (15/17 cases) were statistically significant factors associated with deep vein thrombosis occurrence. Conclusions: The risk of deep vein thrombosis in patients with major lower limb fractures is significant and increases with underlying conditions, hospital stay duration, and fracture location. Therefore, prophylactic deep vein thrombosis treatment before and after surgery is essential.

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References

1. Azarbal A, Duplex ultrasound screening detects high rates of deep vein thromboses in critically ill trauma patients. J Vasc Surg. 2011 Sep;54(3): 743-7; discussion 747-8
2. Linqin Wu, Analysis of perioperative risk factors for deep vein thrombosis in patients with femoral and pelvic fractures. J Orthop Surg Res. 2020 Dec 10;15(1):597
3. Piovella F - AIDA study, Deep-vein thrombosis rates after major orthopedic surgery in Asia. An epidemiological study based on postoperative screening with centrally adjudicated bilateral venography, J Thromb Haemost; 3: 2664–70.
4. Hu Wang, et al, Perioperative incidence and locations of deep vein thrombosis following specific isolated lower extremity fractures. Injury. 2018 Jul;49(7):1353-1357
5. Zhao WG, Characteristics of Deep Venous Thrombosis in Isolated Lower Extremity Fractures and Unsolved Problems in Guidelines: A Review of Recent Literature. Orthop Surg. 2022 Aug;14(8):1558-1568
6. Seung-Ick Cha, et al, Venous Thromboembolism in Korean Patients Undergoing Major Orthopedic Surgery: A Prospective Observational Study using Computed Tomographic (CT) Pulmonary Angiography and Indirect CT Venography. J Korean Med Sci. 2010 Jan;25(1):28-34.
7. Wang T, Risk factors for preoperative deep venous thrombosis in hip fracture patients: a meta-analysis. J Orthop Traumatol. 2022 Apr 7;23(1):19
8. Qiang Li, Analysis of the occurrence of deep venous thrombosis in lower extremity fractures: A clinical study. Pak J Med Sci. 2018 Jul-Aug;34(4):828-832