ASSOCIATION BETWEEN METABOLIC ASSOCIATED FATTY LIVER DISEASE AND ATHEROSCLEROTIC LOWER EXTREMITY ARTERIAL DISEASE IN PATIENTS WITH TYPE 2 DIABETES MELLITUS

Thiện Nhân Chung, Hồng Minh Công Võ , Thị Thùy Dung Ngô

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Abstract

Objective: To determine the association between metabolic associated fatty liver disease (MAFLD) and atherosclerotic lower extremity arterial disease (LEAD) in patients with type 2 diabetes mellitus. Methods: A cross-sectional study was conducted on 212 type 2 diabetes mellitus patients at Gia Dinh People’s Hospital and Thong Nhat Hospital in 2024. Results: The prevalence of MAFLD in the study population was 71.2%. Atherosclerotic plaques in lower extremity arteries were more frequently observed in patients with MAFLD (p = 0.003); however, no significant difference was found in the prevalence of LEAD between groups (p >0.050). Multivariate logistic regression analysis showed that MAFLD increased the risk of developing atherosclerotic plaques in the lower extremity arteries in T2DM patients, with an odds ratio (OR) of 2.83 (95% CI: 1.45 – 5.53, p = 0.002). Conclusion: MAFLD is associated with the presence of atherosclerotic plaques in the lower extremity arteries but not with LEAD in patients with type 2 diabetes mellitus.

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References

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