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Date Published: 11/03/2026
Abstract Views: 23
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DOI: https://doi.org/10.51298/vmj.v559i3.17671
Issue
Vol. 559 No. 3 (2026)
Section
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How to Cite
Lê, V. T., Đoàn, S., & Dương, H. K. L. (2026). INVESTIGATING THE ROLE OF TROPONIN IN THE PREDICTION AND PROGNOSIS OF ATRIAL FIBRILLATION: A SYSTEMATIC REVIEW ACCORDING TO PRISMA. Vietnam Medical Journal, 559(3). https://doi.org/10.51298/vmj.v559i3.17671

INVESTIGATING THE ROLE OF TROPONIN IN THE PREDICTION AND PROGNOSIS OF ATRIAL FIBRILLATION: A SYSTEMATIC REVIEW ACCORDING TO PRISMA

Văn Thanh Lê, Sang Đoàn, Hà Khánh Linh Dương

Main Article Content

Abstract

Objective: This systematic review (according to PRISMA) assesses the role of troponin in predicting new-onset atrial fibrillation (AF) and prognosis in patients with established AF. Methods: We analyzed 35 studies (including cohort studies and meta-analyses) identified from the MEDLINE, Scopus, and Cochrane databases. Results: Regarding prediction: Elevated high-sensitivity troponin (hs-cTn) concentrations were strongly and dose-dependently associated with the risk of developing new-onset AF, even after adjusting for traditional risk factors. Regarding prognosis: In patients with established AF (especially in the emergency department), elevated troponin was a strong prognostic factor. A meta-analysis showed a significantly increased risk of all-cause mortality (Pooled HR 2.7) and Major Adverse Cardiac Events (MACE) (Pooled HR 2.17). Conclusion: Troponin is an important biomarker. It acts as an early warning system for new-onset AF (reflecting subclinical atrial injury) and is a powerful prognostic tool for identifying high-risk AF patients.

Article Details

Keywords

Atrial Fibrillation, Troponin, Prediction, Prognosis, Systematic Review

References

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