HIỆU QUẢ GIẢM ĐAU CỦA PHỐI HỢP DEXAMETHASONE TĨNH MẠCH VỚI GÂY TÊ KHOANG MẠC CHẬU SAU PHẪU THUẬT THAY KHỚP HÁNG

Abstract

Background: There have been few studies showed efficacy of combination of intravenous dexamethasone and fasia iliaca plane block for hip arthroplasty. The aim of this study was to determine effect of dexamethasone on duration of analgesia of fascia iliaca plane block for hip arthroplasty. Methods: This was a prospective cohort study, including 60 participants divided into two groups. Participants who received 8 mg intravenous dexamethasone and fascia iliaca plane block were allocated into group D. Participants who only received fascia iliaca plane block were allocated into group C. 30 mL of ropivacaine 0,2% were injected into fasica iliaca plane in both group under ultrasound guidance. Main outcome was duration of analgesia. Secondary outcomes were postoperative nausea and vomiting, hyperglycemia, quadricep weakness, pain location, pain score and total tramadol consumption. Results: The difference of demographic and surgical characteristics of two group were not significant. Duration of analgesia in group D was longer than that in group C (8.7 (6.9 – 24) hours versus 6.6 (5.9 – 7.8) hours; p < 0.01). None of the participants experienced postoperative nausea and vomiting. There were no difference in incidence of hyperglycemia, quadricep weakness and localized pain claim. There were also no difference in pain score both at rest and in movement at all recorded time. Total 24-hour tramadol consumption in group D was lower than that in group C, 45 ± 6.5 và 65.0 ± 5.9 (p = 0.02). Conclusion: The combination of 8 mg intravenous dexamethasone with fascia iliaca block were effective in prolonging 30% of duration of analgesia after hip arthroplasty.