ĐÁNH GIÁ ĐẶC ĐIỂM HÌNH THÁI TUYẾN ỨC Ở NGƯỜI VIỆT NAM TRƯỞNG THÀNH BẰNG CẮT LỚP VI TÍNH

Abstract

Objective: Evaluation of the morphological characteristics and fatty involution of the thymus in adult Vietnamese by sex and age. Subjects and Methods: A total of 378 Vietnamese subjects, aged ≥18 years, who underwent chest computed tomography (CT) with or without contrast enhancement at the Department of  Diagnostic Imaging, Nguyen Trai Hospital, from November 2024 to September 2025. Results – Conclusion: The study included 378 cases who underwent CT scans. The mean age was 60,98 ± 16,14 years, with a male-to-female ratio of 1:1,16 (46,3% and 53,7%). Among the 378 participants, the distribution of the visual thymic involution score was as follows Score 0 (complete fatty replacement, soft tissue density no longer definable) accounted for the highest proportion with 219 cases (57,9%), Score 1 (thymus predominantly fat) had 80 cases (21,2%), Score 2 (thymus consisting of approximately half fat and half soft tissue) accounted for 40 cases (10,6%), Score 3 (thymus predominantly soft tissue) accounted for 39 cases (10,3%), nearly equivalent to Score 2. The results showed that the visual thymic score distribution between males and females was not statistically significantly different (p>0,05). The evaluation of the visual thymic score demonstrated that an increase in age resulted in a corresponding decrease in the visual thymic score, and this difference was statistically significant (p<0,001). Assessing the influence of age and sex on the degree of thymic fatty involution, the study recorded that for every one-year increase in age, the degree of thymic fatty involution increased by 1,153 times, which was statistically significant (p<0,001). Regarding sex, males had a degree of thymic fatty involution 1,439 times higher than females, however, this finding was not statistically significant.