Article Sidebar
Views pdf: 16
THE CORRELATION BETWEEN MATERNAL UREAPLASMA INFECTION AND EARLY NEONATE INFECTIONS
Main Article Content
Abstract
Objective: To investigate the association between maternal Ureaplasma infection during pregnancy and neonatal morbidity at Vinmec Times City International Hospital over a two-year period, from January 2023 to December 2024. Subjects and Methods: The study included 146 pregnant women who tested positive for Ureaplasma and 154 pregnant women who tested negative, along with their newborns, at Vinmec Times City International Hospital between January 1, 2023, and December 31, 2024. Results: Ureaplasma spp. infection was found to be associated with maternal urinary tract infections (p< 0.05). Treatment with Azithromycin in women infected with Ureaplasma was statistically significantly correlated with a higher rate of neonatal infections (p < 0.05). U. parvum was found to have a greater impact than U. urealyticum on the incidence of neonatal respiratory distress syndrome (p = 0.02). Conclusion: Ureaplasma infection during pregnancy may be associated with maternal urinary tract infection as well as early-onset neonatal infection. U. parvum may play a more important pathogenic role than U. urealyticum in the development of neonatal respiratory distress syndrome
Article Details
Keywords
Ureaplasma spp., maternal urinary tract infection, neonatal infection, neonatal respiratory distress syndrome
References
2. Goldenberg RL, Culhane JF, Iams JD, et al. Epidemiology and causes of preterm birth. Lancet. 2008; 371: 75 - 84.
3. Rittenschober-Böhm J, Waldhoer T, Schulz SM, et al. Vaginal Ureaplasma parvum serovars and spontaneous preterm birth. Am J Obstet Gynecol. 2019; June; 220(6):594.e1 - 594.e9.
4. Kacerovský M, Boudys L. Preterm premature rupture of membranes and Ureaplasma urealyticum. Ceska Gynekol. 2008; 73(3): 154 - 159.
5. Daiva Bartkeviciene, Gina Opolskiene, Agne Bartkeviciute. The impact of Ureaplasma infections on pregnancy complications. Libyan J Med. 2020 Aug 28; 15(1):1812821.
6. Donders GG, Van Calsteren C, Bellen G, et al. Association between abnormal vaginal flora and cervical length as risk factors for preterm birth. Ultrasound Obstet Gynecol. 2010.
7. Stamm WE, Running K, Hale J, Holmes KK ex Transm Dis. Etiologic role of Mycoplasma hominis and Ureaplasma urealyticum in women with the acute urethral syndrome. 1983;10(4 Suppl):318]
8. Steel JH, Malatos S, Kennea N, et al. Bacteria and inflammatory cells in fetal membranes do not always cause preterm labor. Pediatr Res. 2005; 57: 404 - 411.