CLINICAL CHARACTERISTICS, PARACLINICAL FINDINGS, AND ENDOSCOPIC FEATURES OF PATIENTS WITH GASTROESOPHAGEAL REFLUX DISEASE AT MY DUC GENERAL HOSPITAL

Văn Thành Bùi , Công Định Lê , Thị Bắc Dương , Thị Thanh Hiên Lê

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Abstract

Objective: To describe the clinical characteristics, paraclinical findings, endoscopic features, and GERD-Q scores of patients with gastroesophageal reflux disease (GERD) at My Duc General Hospital. Subjects and Methods: A cross-sectional descriptive study was conducted on 140 patients diagnosed with GERD and receiving treatment at My Duc General Hospital from April 2025 to September 2025. Results: The mean age of the study population was 52.8 ± 15.2 years. Females accounted for a higher proportion (64.3%) compared to males (35.7%). Patients with normal BMI represented the largest group (68.6%), followed by overweight individuals (22.1%). Most patients had a disease duration of less than 3 years. The most common clinical symptoms were heartburn/regurgitation (100%), epigastric pain (96.42%), and retrosternal burning sensation (69.28%). Symptoms typically occurred intermittently or in episodes. The most frequent risk factors were type 2 diabetes and smoking. Most participants had a GERD-Q score of 7 or higher, with a mean score of 7.02 ± 1.77. According to the Los Angeles classification, grade A esophagitis was most common (82.42%), followed by grade B (17.16%) and grade D (1.42%). The most prevalent associated endoscopic finding was gastroduodenal erosive inflammation (95%). A significant association was observed between a GERD-Q score ≥7 and clinical symptoms such as heartburn/regurgitation, retrosternal burning, as well as risk factors including type 2 diabetes and smoking.

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References

1. El-Serag Hashem B, Stephen Sweet, C Winchester Christopher, et al (2014), "Update on the epidemiology of gastro-oesophageal reflux disease: a systematic review", Gut, 63 (6), 871-880.
2. Quach D. T, Phan B. T (2022), "A Long Duration of Reflux Symptoms is the Predominant Risk Factor for Depression in Vietnamese Patients with Gastroesophageal Reflux Disease", Neuropsychiatr Dis Treat, 18 2141-2150.
3. Fox Mark, Ian Forgacs (2006), "Gastro-oesophageal reflux disease", Bmj, 332 (7533), 88-93.
4. Eusebi Leonardo H, Raguprakash Ratnakumaran, Yuhong Yuan, et al (2018), "Global prevalence of, and risk factors for, gastro-oesophageal reflux symptoms: a meta-analysis", Gut, 67 (3), 430-440.
5. Katz P. O, Dunbar K. B, Schnoll-Sussman F. H, et al (2022), "ACG Clinical Guideline for the Diagnosis and Management of Gastroesophageal Reflux Disease", Am J Gastroenterol, 117 (1), 27-56.
6. Vũ Thị Thu Trang, Phạm Văn Linh (2021), "Đối chiếu đặc điểm lâm sàng với tổn thương thực quản qua nội soi ở bệnh nhân trào ngược dạ dày thực quản tại Bệnh Viện Hữu Nghị Việt Tiệp năm 2021", Tạp chí Y học Việt Nam, Tập 515 (Tháng 6 - Số đặc biệt), Tr 249 - 254.
7. GH Koek et al (2004), Determining factor in the etiology of esophagitis and Barrett's esophagus, Bile reflux in GERD: Pathophysiological mechanism, clinical relevance and therapeutic implications, 144 - 163.
8. Đoàn Thị Hoài (2006), Nghiên cứu đặc điểm lâm sàng, hình ảnh nội soi, mô bệnh học và đo pH thực quản liên tục 24h trong hội chứng trào ngược dạ dày - thực quản, Luận văn thạc sĩ y học, Trường Đại học Y Hà Nội.