Article Sidebar
Views PDF: 15
DESCRIBE OF IMAGING CHARACTERISTICS OF HEPATOCALLULAR CARCINOMA (HCC) ON CT SCAN AND SOME RELATED FACTORS AT SON TAY HOSPITAL
Main Article Content
Abstract
Objective: To describe computed tomography (CT) imaging characteristics of hepatocellular carcinoma (HCC) and associated clinical factors. Methods: A retrospective cross-sectional study of 35 patients diagnosed with HCC according to Vietnamese Ministry of Health guidelines (Decision No. 3129/QD-BYT) who underwent multidetector CT at Son Tay General Hospital from January 1 to December 31, 2024. Results: Solitary tumors accounted for 80%, predominantly located in the right lobe (82.9%). Tumor size >5 cm was observed in 68.6%. Hypodensity before contrast injection was seen in 85.7%. Arterial phase hyperenhancement occurred in 91.4%, while portal venous washout was observed in 88.6%. Portal vein thrombosis was detected in 8.6%. Serum AFP levels >400 ng/mL were present in 68.6%. HBV infection accounted for 51.4% and HCV for 5.7%. AFP levels showed a positive correlation with tumor size (p<0.05). Conclusion: Multidetector CT plays a crucial role in detecting and characterizing HCC. Combining CT imaging features with AFP and viral hepatitis status improves diagnostic accuracy, particularly in regional hospitals.
Article Details
Keywords
Hepatocellular carcinoma, Computed tomography, AFP.
References
1. Ferlay J et al (2008), "Estimates of worldwide burden of cancer in 2008:GLOBOCAN 2008",Int J Cancer
2. Catalano O, Cusati B, Sandomenico F (1999), Multiple-phase spiral computerized tomography of small hepatocellular carcinoma: technique optimization and diagnostic yeild, 98: pp 53-64.
3. B G Choi, S H Park, J Y Byun (2001), The finding of ruptured hepatocellular carcinoma on helical CT, 74: pp 142-146.
4. Ehman EC, Behr SC. Umetsu SE, et al. Rate of observation and inter- observer agreement for LI- RADS major features at CT and MRI in 184 pathology proven hepatocellular carcinomas. Abdom Radiol (NY). 2016:41(5):963-969. doi:10.1007/s00261-015-0623-5
5. Thái Doãn Kỳ (2015), Nghiên cứu kết quả điều trị ung thư biểu mô tế bào gan bằng phương pháp tắc mạch hóa dầu sử dụng hạt vi cầu Dc Beads, Viện nghiên cứu khoa học y dược lâm sàng 108.
6. Trần Thị Hồng Nhung (2020), Đánh giá phân loại LI-RADS trên cắt lớp vi tính đa dãy trong chẩn đoán tổn thương khu trú ở nhu mô gan, Luận văn Thạc sĩ Y học Đại Học Y Hà Nội.
7. Hồ Ngọc Linh, Nguyễn Nam Hùng (2013), "Nghiên cứu đặc điểm hình ảnh chụp CLVT u gan tại Bệnh viện Đa khoa tỉnh Kon Tum từ 2010.
8. Phạm Trường Giang (2021), Tìm hiểu đặc điểm lâm sàng, cận lâm sàng và hình ảnh cắt lớp vi tính ung thư biểu mô tế bào gan (HCC), Khóa luận tốt nghiệp. Y học Đại Học Quốc Gia Hà Nội.